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Low doses of radiation — impact on the environment and human
Affiliations- Nicolaus Copernicus University, Collegium Medicum, Department of Geriatrics, Bydgoszcz, Poland
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Abstract
The health effects of low-dose ionizing radiation are critical in such important fields as X-ray imaging, radiotherapy and nuclear energy. However, all existing and potential applications are being challenged by public concerns and regulatory constraints. The goal was to review the literature in which health damage caused by radiation is assessed. An extensive search on PubMed was made. Particular attention was paid to articles cited in comprehensive reviews of the U.S. National Academy of Sciences and the 2016 report of the United Nations Scientific Committee on Atomic Radiation. Epidemiological data provide essentially no evidence of harmful health effects at doses below 100 mSv, and several studies suggest beneficial effects. There is growing evidence that low-dose radiation, such as that used in X-ray imaging, including computed tomography (CT), has beneficial health effects rather than poses a risk. A common trend observed in many occupationally exposed cohorts worldwide is that their mortality rate is generally lower than that of the general population.
Abstract
The health effects of low-dose ionizing radiation are critical in such important fields as X-ray imaging, radiotherapy and nuclear energy. However, all existing and potential applications are being challenged by public concerns and regulatory constraints. The goal was to review the literature in which health damage caused by radiation is assessed. An extensive search on PubMed was made. Particular attention was paid to articles cited in comprehensive reviews of the U.S. National Academy of Sciences and the 2016 report of the United Nations Scientific Committee on Atomic Radiation. Epidemiological data provide essentially no evidence of harmful health effects at doses below 100 mSv, and several studies suggest beneficial effects. There is growing evidence that low-dose radiation, such as that used in X-ray imaging, including computed tomography (CT), has beneficial health effects rather than poses a risk. A common trend observed in many occupationally exposed cohorts worldwide is that their mortality rate is generally lower than that of the general population.
Keywords
natural radiation, low-dose, nuclear, cancer
About this articleTitle
Low doses of radiation — impact on the environment and human
Journal
Issue
Article type
Review article
Pages
152-158
Published online
2023-04-24
Page views
1388
Article views/downloads
357
DOI
Bibliographic record
Medical Research Journal 2023;8(2):152-158.
Keywords
natural radiation
low-dose
nuclear
cancer
Authors
Szymon Roszkowski
References (60)- Grant EJ, Yamamura M, Brenner AV, et al. Solid Cancer Incidence among the Life Span Study of Atomic Bomb Survivors: 1958-2009. Radiat Res. 2017; 187(5): 513–537.
- Cui J, Yang G, Pan Z, et al. Hormetic response to low-dose radiation: focus on the immune system and its clinical implications. Int J Mol Sci. 2017; 18(2).
- Lumniczky K, Impens N, Armengol G, et al. Low dose ionizing radiation effects on the immune system. Environ Int. 2021; 149: 106212.
- Khan MdG, Wang Yi. Advances in the current understanding of how low-dose radiation affects the cell cycle. Cells. 2022; 11(3).
- Azzam EI, Colangelo NW, Domogauer JD, et al. Is ionizing radiation harmful at any exposure? An echo that continues to vibrate. Health Phys. 2016; 110(3): 249–251.
- Belli M, Tabocchini MA. Ionizing radiation-induced epigenetic modifications and their relevance to radiation protection. Int J Mol Sci. 2020; 21(17).
- Tamada Y, Yamaguchi C, Saito M, et al. Does laughing with others lower the risk of functional disability among older Japanese adults? The JAGES prospective cohort study. Prev Med. 2022; 155: 106945.
- Dublin LI, Spiegelman M. Mortality of medical specialists, 1938 - interventional procedures, 1994–2008. J Am Med Dir Assoc. 2016; 206(5): 1101–1108.
- Doll R, Berrington A, Darby SC. Low mortality of British radiologists. Br J Radiol. 2005; 78(935): 1057–1058.
- Berrington A, Darby SC, Weiss HA, et al. 100 years of observation on British radiologists: mortality from cancer and other causes 1897-1997. Br J Radiol. 2001; 74(882): 507–519.
- Cameron JR. Radiation increased the longevity of British radiologists. Br J Radiol. 2002; 75(895): 637–639.
- Mohan AK, Hauptmann M, Freedman DM, et al. Cancer and other causes of mortality among radiologic technologists in the United States. Int J Cancer. 2003; 103(2): 259–267.
- Kitahara CM, Linet MS, Balter S, et al. Occupational radiation exposure and deaths from malignant intracranial neoplasms of the brain and CNS in U.S. Radiologic technologists, 1983-2012. AJR Am J Roentgenol. 2017; 208(6): 1278–1284.
- Tubiana M. Computed tomography and radiation exposure. N Engl J Med. 2008; 358(8): 850; author reply 852–850; author reply 853.
- Sponsler R, Cameron J. Nuclear shipyard worker study (1980–1988): a large cohort exposed to low-dose-rate gamma radiation. International Journal of Low Radiation. 2005; 1(4): 463.
- Schubauer-Berigan MK, Daniels RD, Bertke SJ, et al. Cancer mortality through 2005 among a pooled cohort of U.S. Nuclear workers exposed to external ionizing radiation. Radiat Res. 2015; 183(6): 620–631.
- Gilbert ES, Fry SA, Wiggs LD, et al. Analyses of combined mortality data on workers at the Hanford Site, Oak Ridge National Laboratory, and rocky flats nuclear weapons plant. Radiat Res. 1989; 120(1): 19.
- Gilbert ES, Cragle DL, Wiggs LD. Updated analyses of combined mortality data for workers at the Hanford Site, Oak Ridge National Laboratory, and Rocky Flats Weapons Plant. Radiat Res. 1993; 136(3): 408–421.
- Boice Jr JD, Cohen SS, Mumma MT, et al. Updated mortality analysis of radiation workers at Rocketdyne (Atomics International), 1948–2008. Radiat Res. 2011; 176(2): 244–258.
- Zablotska LB, Ashmore JP, Howe GR. Analysis of mortality among Canadian nuclear power industry workers after chronic low-dose exposure to ionizing radiation. Radiat Res. 2004; 161(6): 633–641.
- Cardis E, Vrijheid M, Blettner M. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry. Radiat Res. 2007; 167(4): 396–416.
- Vrijheid M, Cardis E, Blettner M, et al. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: design, epidemiological methods and descriptive results. Radiat Res. 2007; 167(4): 361–379.
- Vrijheid M, Cardis E, Ashmore P, et al. 15-Country Study Group. Ionizing radiation and risk of chronic lymphocytic leukemia in the 15-country study of nuclear industry workers. Radiat Res. 2008; 170(5): 661–665.
- Schüz J, Deltour I, Krestinina LY, et al. Incidence and mortality of solid cancers in people exposed in utero to ionizing radiation: pooled analyses of two cohorts from the southern urals, russia. PLoS One. 2016; 11(8): e0160372–133.
- Kreuzer M, Sobotzki C, Fenske N, et al. Leukaemia mortality and low-dose ionising radiation in the WISMUT uranium miner cohort (1946-2013). Occup Environ Med. 2017; 74(4): 252–258.
- Navaranjan G, Berriault C, Do M, et al. Cancer incidence and mortality from exposure to radon progeny among Ontario uranium miners. Occup Environ Med. 2016; 73(12): 838–845.
- Grellier J, Atkinson W, Bérard P, et al. Risk of lung cancer mortality in nuclear workers from internal exposure to alpha particle-emitting radionuclides. Epidemiology. 2017; 28(5): 675–684.
- Rage E, Caër-Lorho S, Laurier D, et al. Mortality analyses in the updated French cohort of uranium miners (1946–2007). Int Arch Occup Environ Health. 2015; 88(6): 717–730.
- Kreuzer M, Sobotzki C, Schnelzer M, et al. Lung cancer risk at low radon exposure rates in German uranium miners. Br J Cancer. 2015; 113(9): 1367–1369.
- Keil AP, Richardson DB, Troester MA. Healthy worker survivor bias in the Colorado Plateau uranium miners cohort. Am J Epidemiol. 2015; 181(10): 762–770.
- Electric Power Research Institute. Program on Technology Innovation: Evaluation of Updated Research on the Health Effects and Risks Associated with Low-Dose Ionizing Radiation. https://www.epri.com/#/pages/product/1019227/?lang=en-US (16.02.2023).
- American Association of Physicists in Medicine. AAPM Position Statement on Radiation Risks from Medical Imaging Procedures. https://www.aapm.org/org/policies/details.asp?id=318&type=PP¤t=true (16.02.2023).
- Tchorz-Trzeciakiewicz DE, Kozłowska B, Walencik-Łata A. Seasonal variations of terrestrial gamma dose, natural radionuclides and human health. Chemosphere. 2023; 310: 136908.
- Hendry JH, Simon SL, Wojcik A, et al. Human exposure to high natural background radiation: what can it teach us about radiation risks? J Radiol Prot. 2009; 29(2A): A29–A42.
- BEIR (Biological Effects of Ionizing Radiation) VII Phase 2 Report. Health Risks from Exposure to Low Levels of Ionizing Radiation. National Research Council. The National Academy Press, Washington 2006.
- Ishihara H, Ohno Y, Fujii M, et al. Epidemiological analysis of childhood cancer in Japan based on population-based cancer registries, 1993-2009. Jpn J Clin Oncol. 2017; 47(7): 660–663.
- Boice JD, Cohen SS, Mumma MT, et al. Mortality among U.S. military participants at eight aboveground nuclear weapons test series. Int J Radiat Biol. 2022; 98(4): 679–700.
- Hart J, Hyun S. Cancer mortality, state mean elevations, and other selected predictors. Dose Response. 2012; 10(1): 58–65.
- Muirhead CR, O'Hagan JA, Haylock RGE, et al. Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers. Br J Cancer. 2009; 100(1): 206–212.
- Hart J. Cancer mortality for a single race in low versus high elevation counties in the u.s. Dose Response. 2011; 9(3): 348–355.
- Hart J. Heart disease death rates in low versus high land elevation counties in the U.S. Dose Response. 2015; 13(1).
- Allwright SP, Colgan PA, McAulay IR, et al. Natural background radiation and cancer mortality in the Republic of Ireland. Int J Epidemiol. 1983; 12(4): 414–418.
- Health survey in high background radiation areas in China: High Background Radiation Research Group, China . Science. 1980; 209(4459): 877–880.
- Tao Z, Zha Y, Akiba S, et al. Cancer mortality in the high background radiation areas of Yangjiang, China during the period between 1979 and 1995. J Radiat Res. 2000; 41 Suppl: 31–41.
- Nair RR, Rajan B, Akiba S, et al. Background radiation and cancer incidence in Kerala, India-Karanagappally cohort study. Health Phys. 2009; 96(1): 55–66.
- Cameron JR. Moderate dose rate ionizing radiation increases longevity. Br J Radiol. 2005; 78(925): 11–13.
- Körblein A, Hoffmann W. Background radiation and cancer mortality in Bavaria: an ecological analysis. Arch Environ Occup Health. 2006; 61(3): 109–114.
- Han YY, Youk AO, Sasser H, et al. Cancer incidence among residents of the Three Mile Island accident area: 1982–1995. Environ Res. 2011; 111(8): 1230–1235.
- Talbott EO, Youk AO, McHugh-Pemu KP, et al. Long-term follow-up of the residents of the Three Mile Island accident area: 1979-1998. Environ Health Perspect. 2003; 111(3): 341–348.
- United Nations Scientific Committee on the Effects of Atomic Radiation. Annex D. Health effects due to radiation from the Chernobyl accident. In: Sources and Effects of Ionizing Radiation, UNSCEAR 2008 Report to the General Assembly, with Scientific Annexes. United Nations, New Yorsk 2010: 151–186.
- Williams D, Williams D. Cancer after nuclear fallout: lessons from the Chernobyl accident. Nat Rev Cancer. 2002; 2(7): 543–549.
- Kazakov VS, Demidchik EP, Astakhova LN. Thyroid cancer after Chernobyl. Nature. 1992; 359(6390): 21.
- Cardis E, Kesminiene A, Ivanov V, et al. Risk of Thyroid Cancer After Exposure to 131 I in Childhood. J Natl Cancer Inst. 2005; 97(10): 724–732.
- Cardis E, Howe G, Ron E, et al. Cancer consequences of the Chernobyl accident: 20 years on. J Radiol Prot. 2006; 26(2): 127–140.
- Takamura N, Yamashita S, et al. Lessons from Chernobyl. Fukushima J Med Sci. 2011; 57(2): 81–85.
- Imanaka T, Hayashi G, Endo S. Comparison of the accident process, radioactivity release and ground contamination between Chernobyl and Fukushima-1. J Radiat Res. 2015; 56 Suppl 1(Suppl 1): i56–i61.
- Suzuki S, Suzuki S, Fukushima T, et al. Comprehensive survey results of childhood thyroid ultrasound examinations in Fukushima in the first four years after the Fukushima Daiichi Nuclear Power Plant accident. Thyroid. 2016; 26(6): 843–851.
- Hasegawa A, Ohira T, Maeda M, et al. Emergency responses and health consequences after the Fukushima accident; evacuation and relocation. Clin Oncol (R Coll Radiol). 2016; 28(4): 237–244.
- Calabrese EJ, Yazji Shamoun D, Agathokleous E. Dose response and risk assessment: evolutionary foundations. Environ Pollut. 2022; 309: 119787.
- David E, Bitan R, Atlas S, et al. Correlative links between natural radiation and life expectancy in the US population. Biogerontology. 2022; 23(4): 425–430.