open access

Vol 7, No 3 (2022)
Case report
Published online: 2022-07-26
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Angiosarcoma of the lungs, liver, and bones in a 27-year-old male patient

Melania Mikołajczyk-Solińska1, Tomasz Szpotan2, Agata Majos2, Marcin Braun3, Jacek Musiał3, Radzisław Kordek3, Jacek Kasznicki1
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Medical Research Journal 2022;7(3):256-261.
Affiliations
  1. Department of Internal Medicine, Diabetology and Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
  2. Department of Radiological and Isotopic Diagnosis and Therapy, Medical University of Lodz, Lodz, Poland
  3. Department of Pathology, Chair of Oncology, Medical University of Lodz, Lodz, Poland

open access

Vol 7, No 3 (2022)
CASE REPORTS
Published online: 2022-07-26

Abstract

Angiosarcoma is a rare (from 1% to 2% of all soft tissue sarcomas), highly aggressive endothelial tumor that may affect any organ. The prognosis for the disease is poor, particularly if it is metastatic by the time of diagnosis. The etiology is unclear; however, there are definite risk factors including chronic lymphedema, radiation therapy, familial syndromes, and exposure to environmental chemical toxins and foreign bodies. Although the final diagnosis is histopathological, radiological tools such as ultrasound, CT, and MRI are still necessary to determine the stage of cancer. Treatment includes surgery, chemotherapy, and radiation therapy. Chemotherapy is the main treatment strategy for metastatic angiosarcoma, however, the toxicity level of frequently used agents is high. The research focuses on targeted medicines and immunotherapy as potential therapeutic options. We present a case of angiosarcoma in a young man without chronic illnesses with metastatic spread to the lungs, liver, and bones at the time of diagnosis

Abstract

Angiosarcoma is a rare (from 1% to 2% of all soft tissue sarcomas), highly aggressive endothelial tumor that may affect any organ. The prognosis for the disease is poor, particularly if it is metastatic by the time of diagnosis. The etiology is unclear; however, there are definite risk factors including chronic lymphedema, radiation therapy, familial syndromes, and exposure to environmental chemical toxins and foreign bodies. Although the final diagnosis is histopathological, radiological tools such as ultrasound, CT, and MRI are still necessary to determine the stage of cancer. Treatment includes surgery, chemotherapy, and radiation therapy. Chemotherapy is the main treatment strategy for metastatic angiosarcoma, however, the toxicity level of frequently used agents is high. The research focuses on targeted medicines and immunotherapy as potential therapeutic options. We present a case of angiosarcoma in a young man without chronic illnesses with metastatic spread to the lungs, liver, and bones at the time of diagnosis

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Keywords

angiosarcoma, metastases, etiology, diagnostic tools, treatment, prognosis

About this article
Title

Angiosarcoma of the lungs, liver, and bones in a 27-year-old male patient

Journal

Medical Research Journal

Issue

Vol 7, No 3 (2022)

Article type

Case report

Pages

256-261

Published online

2022-07-26

Page views

4003

Article views/downloads

508

DOI

10.5603/MRJ.a2022.0030

Bibliographic record

Medical Research Journal 2022;7(3):256-261.

Keywords

angiosarcoma
metastases
etiology
diagnostic tools
treatment
prognosis

Authors

Melania Mikołajczyk-Solińska
Tomasz Szpotan
Agata Majos
Marcin Braun
Jacek Musiał
Radzisław Kordek
Jacek Kasznicki

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