Vol 6, No 3 (2021)
Original article
Published online: 2021-09-21

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Functioning of patients with post-COVID syndrome — preliminary data

Aldona Kubica1, Piotr Michalski1, Michał Kasprzak2, Przemysław Podhajski2, Łukasz Pietrzykowski1, Alicja Rzepka-Cholasińska1, Tomasz Fabiszak2, Jacek Kryś3
Medical Research Journal 2021;6(3):224-229.


Introduction: Post-COVID syndrome is a common finding during the first year after SARS-CoV-2 infection affecting the daily living of many patients. The aim of this study was to assess the functioning of patients with post-COVID syndrome.

Material and methods: A self-reported questionnaire — the Functioning in Chronic Illness Scale (FCIS) — was applied in 79 (30 women, 49 men) patients (mean age of 62.7 ± 13.6 years), suffering from post- COVID syndrome 5.8 ± 2.3 months after discharge from hospital.

Results: The mean FCIS score was 86.2 ± 12.8 points, corresponding to medium functioning level. The mean score in the first, second and third subscale was 27.0 ± 6.4; 27.5 ± 3.7; and 31.7 ± 4.3 points respectively. Better functioning was observed in men vs women: the FCIS score 88.59 ± 10.95 vs 82.20 ± 14.71; p = 0.02 and in the youngest patients: first ( < 59 years) vs second (59–67 years) vs third tercile ( > 67 years): FCIS score 92.76 ± 14.84 vs 83.15 ± 11.64 vs 83.07 ± 9.68; p = 0.01). The amount of time from COVID-19-related hospitalisation did not affect the FCIS score.

Conclusion: Symptoms of post-COVID syndrome influencing patients’ functioning persist within the first year regardless of the time elapsing from the disease. Men and younger patients demonstrate better functioning abilities.

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  1. Carfì A, Bernabei R, Landi F, et al. Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020; 324(6): 603–605.
  2. Mo X, Jian W, Su Z, et al. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J. 2020; 55(6): 2001217.
  3. Wei J, Yang H, Lei P, et al. Analysis of thin-section CT in patients with coronavirus disease (COVID-19) after hospital discharge. Journal of X-Ray Science and Technology. 2020; 28(3): 383–389.
  4. Mandal S, Barnett J, Brill SE, et al. ARC Study Group. 'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. Thorax. 2021; 76(4): 396–398.
  5. Yelin D, Margalit I, Yahav D, et al. Long COVID-19-it's not over until? Clin Microbiol Infect. 2021; 27(4): 506–508.
  6. World Health Organization. Noncommunicable Diseases (2016). http://www.who.int/topics/noncommunicable_diseases/en/ (13.09.2021).
  7. MedicineNet. Definition of Chronic Disease (2016). http://www.medicinenet.com/script/main/art.asp?articlekey=33490 (13.09.2021).
  8. Kubica A. Self-reported questionnaires for a comprehensive assessment of patients after acute coronary syndrome. Medical Research Journal. 2019; 4(2): 106–109.
  9. Michalski P, Kasprzak M, Kosobucka A, et al. Sociodemographic and clinical determinants of the functioning of patients with coronary artery disease. Medical Research Journal. 2021; 6(1): 21–27.
  10. Kosobucka A, Michalski P, Pietrzykowski Ł, et al. The impact of readiness to discharge from hospital on adherence to treatment in patients after myocardial infarction. Cardiol J. 2020 [Epub ahead of print].
  11. Kubica A, Bączkowska A. Uzasadnienie interwencji motywacyjnych jako kluczowego elementu projektu wielopoziomowej edukacji i motywacji u pacjentów z zawałem serca (MEDMOTION). Folia Cardiologica. 2020; 15(1): 6–10.
  12. Buszko K, Pietrzykowski Ł, Michalski P, et al. Validation of the Functioning in Chronic Illness Scale (FCIS). Medical Research Journal. 2018; 3(2): 63–69.
  13. Kubica A, Kosobucka A, Michalski P, et al. Self-reported questionnaires for assessment adherence to treatment in patients with cardiovascular diseases. Medical Research Journal. 2018; 2(4): 115–122.
  14. Demeco A, Marotta N, Barletta M, et al. Rehabilitation of patients post-COVID-19 infection: a literature review. J Int Med Res. 2020; 48(8): 300060520948382.
  15. Belli S, Balbi B, Prince I, et al. Low physical functioning and impaired performance of activities of daily life in COVID-19 patients who survived hospitalisation. Eur Respir J. 2020; 56(4): 2002096.
  16. Huang C, Huang L, Yao Q, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021; 397(10270): 220–232.
  17. Agostini F, Mangone M, Ruiu P, et al. Rehabilitation setting during and after Covid-19: An overview on recommendations. J Rehabil Med. 2021; 53(1): jrm00141.
  18. Pietrzykowski Ł, Michalski P, Kosobucka A, et al. Knowledge about health and disease in obese patients after myocardial infarction. An observational study. Medical Research Journal. 2018; 2(4): 135–140.
  19. Michalski P, Kosobucka A, Pietrzykowski Ł, et al. Effectiveness of therapeutic education in patients with myocardial infarction. Medical Research Journal. 2018; 2(3): 89–96.
  20. Kubica A, Gruchała M, Jaguszewski M, et al. Adherence to treatment — a pivotal issue in long-term treatment of patients with cardiovascular diseases. An expert standpoint. Medical Research Journal. 2017; 2(4): 123–127.
  21. Kubica A, Adamski P, Bączkowska A, et al. The rationale for Multilevel Educational and Motivational Intervention in Patients after Myocardial Infarction (MEDMOTION) project is to support multicentre randomized clinical trial Evaluating Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome (ELECTRA – SIRIO 2). Medical Research Journal. 2020; 5(4): 244–249.
  22. Michalski P, Kasprzak M, Siedlaczek M, et al. The impact of knowledge and effectiveness of educational intervention on readiness for hospital discharge and adherence to therapeutic recommendations in patients with acute coronary syndrome. Medical Research Journal. 2020; 5(2): 72–78.
  23. Kosobucka A, Kasprzak M, Michalski P, et al. Relation of the Readiness for Hospital Discharge after Myocardial Infarction Scale to socio-demographic and clinical factors. An observational study. Medical Research Journal. 2018; 3(1): 32–37.
  24. Buszko K, Kosobucka A, Michalski P, et al. The readiness for hospital discharge of patients after acute myocardial infarction: a new self-reported questionnaire. Medical Research Journal. 2017; 2(1): 20–28.
  25. Pietrzykowski Ł, Kasprzak M, Michalski P, et al. The influence of patient expectations on adherence to treatment regimen after myocardial infarction. Patient Educ Couns. 2021 [Epub ahead of print].
  26. Pietrzykowski Ł, Kasprzak M, Michalski P, et al. Therapy discontinuation after myocardial infarction. J Clin Med. 2020; 9(12): 4109.
  27. Pietrzykowski Ł, Michalski P, Kosobucka A, et al. Medication adherence and its determinants in patients after myocardial infarction. Sci Rep. 2020; 10(1): 12028.
  28. Kubica A, Kosobucka A, Fabiszak T, et al. Assessment of adherence to medication in patients after myocardial infarction treated with percutaneous coronary intervention. Is there a place for newself-reported questionnaires? Curr Med Res Opin. 2019; 35(2): 341–349.
  29. Kosobucka A, Michalski P, Pietrzykowski Ł, et al. Adherence to treatment assessed with the Adherence in Chronic Diseases scale in patients after myocardial infarction. Patient Prefer Adherence. 2018; 12: 333–340.
  30. Kubica A, Obońska K, Fabiszak T, et al. Adherence to antiplatelet treatment with P2Y12 receptor inhibitors. Is there anything we can do to improve it? A systematic review of randomized trials. Curr Med Res Opin. 2016; 32(8): 1441–1451.
  31. Kubica A, Obońska K, Kasprzak M, et al. Prediction of high risk of non-adherence to antiplatelet treatment. Kardiol Pol. 2016; 74(1): 61–67.
  32. Kubica A, Kasprzak M, Obońska K, et al. Discrepancies in assessment of adherence to antiplatelet treatment after myocardial infarction. Pharmacology. 2015; 95(1-2): 50–58.
  33. Kubica A, Kasprzak M, Siller-Matula J, et al. Time-related changes in determinants of antiplatelet effect of clopidogrel in patients after myocardial infarction. Eur J Pharmacol. 2014; 742: 47–54.