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Diagnostic and therapeutic procedures in gout
Affiliations- Department of Rheumatology and Connective Tissue Diseases, University Hospital no.2 in Bydgoscz, 85-168 Bydgoszcz, Poland
- Medycyna Kliniczna, Warszawa, Poland
- Department of Rheumatology and Connective Tissue Diseases, Collegium Medicum UMK in Toruń, University Hospital No. 2 in Bydgoszcz, 85-168 Bydgoszcz, Poland
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Abstract
Gout, a rheumatic disease caused by crystals (crystal arthropathy), is a form of inflammatory arthritis caused
by monosodium urate depositing in the synovial fluid and as time goes by outside the joints as well (in
other tissues and organs).Gout attacks are sudden and often result from a dietary mistake. In 2015 the
European and American Rheumatological Associations (EULAR and ACR) published joint classification
criteria for gout. The criteria involve gout-specific clinical symptoms, irregular results of laboratory tests
and lesions visible in imaging tests. The “golden standard” of diagnostics still remains the presence of uric
acid crystals in a sample of synovial fluid, the contents of the bursa and of the gouty tophus. The course of
treatment for patients with gout depends on the stage of the disease, but it comes down to implementing
various forms of preventing hyperuricemia by modifying the patient’s lifestyle and diet, reducing risk factors
(such as overweight and obesity) and pharmacological treatment, both in-between and during attacks.
Abstract
Gout, a rheumatic disease caused by crystals (crystal arthropathy), is a form of inflammatory arthritis caused
by monosodium urate depositing in the synovial fluid and as time goes by outside the joints as well (in
other tissues and organs).Gout attacks are sudden and often result from a dietary mistake. In 2015 the
European and American Rheumatological Associations (EULAR and ACR) published joint classification
criteria for gout. The criteria involve gout-specific clinical symptoms, irregular results of laboratory tests
and lesions visible in imaging tests. The “golden standard” of diagnostics still remains the presence of uric
acid crystals in a sample of synovial fluid, the contents of the bursa and of the gouty tophus. The course of
treatment for patients with gout depends on the stage of the disease, but it comes down to implementing
various forms of preventing hyperuricemia by modifying the patient’s lifestyle and diet, reducing risk factors
(such as overweight and obesity) and pharmacological treatment, both in-between and during attacks.
Keywords
gout, arthritis, crystal arthropathy, hyperuricemia, flares of joint inflammation, tophaceous gout, gouty tophi, Colchicine
About this articleTitle
Diagnostic and therapeutic procedures in gout
Journal
Issue
Article type
Review article
Pages
95-98
Published online
2019-03-18
Page views
2252
Article views/downloads
1763
DOI
Bibliographic record
Medical Research Journal 2019;4(2):95-98.
Keywords
gout
arthritis
crystal arthropathy
hyperuricemia
flares of joint inflammation
tophaceous gout
gouty tophi
Colchicine
Authors
Rafał Wojciechowski
Kinga Kościńska-Ilczyszyn
Marzena Waszczak-Jeka
Sławomir Jeka
References (8)- Dalbeth N, So A. Hyperuricaemia and gout: state of the art and future perspectives. Ann Rheum Dis. 2010; 69(10): 1738–1743.
- Zimmermann-Górska I. Postępowanie diagnostyczno-terapeutyczne w chorobach wywoływanych przez kryształy. Reumatologia. 2012; 50: 177–180.
- Neogi T, Jansen TL, Dalbeth N, et al. 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2015; 74(10): 1789–1798.
- , et alet al.. Arthritis & Rheumatology. 2015; 67(10): 2557–2568.
- Maślińska M. Gout and calcium pyrophosphate dihydrate deposition disease. Reumatologia/Rheumatology Supplements. ; 2016: 105–109.
- Bridgeman MB, Chavez B. Febuxostat for the treatment of gout. Expert Opin Pharmacother. 2015; 16(3): 395–398.
- Zimmermann-Górska I, Tuchocka-Kaczmarek A, Goncerz G. Rozpoznanie i leczenie dny moczanowej. Podsumowanie zaleceń międzynaorodwej grupy reumatologów w ramach inicjatywy 3e. Medycyna Praktyczna. 2014; 5: 61–65.
- Zimmermann-Górska I. Dna moczanowa. Interna Szczeklika Gajewski P. (red. Medycyna Praktyczna, Kraków. ; 2018.