open access

Vol 4, No 2 (2019)
Case report
Published online: 2019-03-12
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Cardiovascular effects of cocaine

Michał Siedlaczek1
·
Medical Research Journal 2019;4(2):110-115.
Affiliations
  1. Department of Health Promotion, Nicolaus Copernicus University, Collegium Medicum

open access

Vol 4, No 2 (2019)
CASE REPORTS
Published online: 2019-03-12

Abstract

A case of a 39-year-old man, who was taking cocaine 2-3 times a week for several years. The article contains
the possible impact of cocaine use on the cardiovascular system and differential diagnosis in this patient.

Abstract

A case of a 39-year-old man, who was taking cocaine 2-3 times a week for several years. The article contains
the possible impact of cocaine use on the cardiovascular system and differential diagnosis in this patient.

Get Citation

Keywords

cocaine, cardiovascular

About this article
Title

Cardiovascular effects of cocaine

Journal

Medical Research Journal

Issue

Vol 4, No 2 (2019)

Article type

Case report

Pages

110-115

Published online

2019-03-12

Page views

2522

Article views/downloads

1522

DOI

10.5603/MRJ.a2019.0012

Bibliographic record

Medical Research Journal 2019;4(2):110-115.

Keywords

cocaine
cardiovascular

Authors

Michał Siedlaczek

References (24)
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  3. Kolodgie FD, Virmani R, Cornhill JF, et al. Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. J Am Coll Cardiol. 1991; 17(7): 1553–1560.
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  5. Hollander JE, Hoffman RS, Gennis P, et al. Prospective multicenter evaluation of cocaine-associated chest pain. Cocaine Associated Chest Pain (COCHPA) Study Group. Acad Emerg Med. 1994; 1(4): 330–339.
  6. Weber JE, Chudnofsky CR, Boczar M, et al. Cocaine-associated chest pain: how common is myocardial infarction? Acad Emerg Med. 2000; 7(8): 873–877.
  7. Bosch X, Loma-Osorio P, Guasch E, et al. Prevalence, clinical characteristics and risk of myocardial infarction in patients with cocaine-related chest pain. Rev Esp Cardiol. 2010; 63(9): 1028–1034.
  8. Anderson JL, Adams CD, Antman EM, et al. American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. 2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013; 127(23): e663–e828.
  9. Rangel C, Shu RG, Lazar LD, et al. Beta-blockers for chest pain associated with recent cocaine use. Arch Intern Med. 2010; 170(10): 874–879.
  10. McCord J, Jneid H, Hollander JE, et al. American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. Circulation. 2008; 117(14): 1897–1907.
  11. Su J, Li J, Li W, et al. Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension. Int J Toxicol. 2004; 23(4): 233–237.
  12. Cerretani D, Fineschi V, Bello S, et al. Role of oxidative stress in cocaine-induced cardiotoxicity and cocaine-related death. Curr Med Chem. 2012; 19(33): 5619–5623.
  13. Pitts WR, Vongpatanasin W, Cigarroa JE, et al. Effects of the intracoronary infusion of cocaine on left ventricular systolic and diastolic function in humans. Circulation. 1998; 97(13): 1270–1273.
  14. Freeman K, Feldman JA. Cocaine, myocardial infarction, and beta-blockers: time to rethink the equation? Ann Emerg Med. 2008; 51(2): 130–134.
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  16. Wood DM, Dargan PI. Putting cocaine use and cocaine-associated cardiac arrhythmias into epidemiological and clinical perspective. Br J Clin Pharmacol. 2010; 69(5): 443–447.
  17. Hoffman RS. Treatment of patients with cocaine-induced arrhythmias: bringing the bench to the bedside. Br J Clin Pharmacol. 2010; 69(5): 448–457.
  18. Lakkireddy D, Kanmanthareddy A, Biria M, et al. Radiofrequency ablation of drug refractory ventricular tachycardia related to cocaine use: a feasibility, safety, and efficacy study. J Cardiovasc Electrophysiol. 2014; 25(7): 739–746.
  19. Bauman J, Grawe J, Winecoff A, et al. Cocaine-Related Sudden Cardiac Death: A Hypothesis Correlating Basic Science and Clinical Observations. The Journal of Clinical Pharmacology. 2013; 34(9): 902–911.
  20. Frontera JA, Gradon JD. Right-side endocarditis in injection drug users: review of proposed mechanisms of pathogenesis. Clin Infect Dis. 2000; 30(2): 374–379.
  21. Westover AN, McBride S, Haley RW. Stroke in young adults who abuse amphetamines or cocaine: a population-based study of hospitalized patients. Arch Gen Psychiatry. 2007; 64(4): 495–502.
  22. Kolodgie FD, Virmani R, Cornhill JF, et al. Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. J Am Coll Cardiol. 1991; 17(7): 1553–1560.
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