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2024 ESC Guidelines on the treatment of chronic coronary syndrome — unanswered questions regarding antianginal medical therapy recommendations. A position paper of the ELECTRA-SIRIO 2 investigators

Jacek Kubica123, Piotr Adamski1, Piotr Buszman45, Tomasz Fabiszak1, Jakub Foryś6, Robert Gajda7, Mariusz Gasior89, Marek Gierlotka10, Robert Gil11, Tomasz Hajdukiewicz12, Miłosz Jaguszewski13, Piotr Jankowski14, Wacław Kochman15, Jacek Konarski2, Aldona B. Kubica163, Wiktor Kuliczkowski17, Ewa Laskowska16, Maciej Lesiak18, Przemysław Magielski19, Piotr Michalski16, Przemysław Mitkowski20, Natalia Mrzywka21, Eliano Pio Navarese22, Piotr Niezgoda16, Małgorzata Ostrowska16, Maciej Piasecki162, Przemysław Podhajski16, Alicja Rzepka-Cholasińskia1, Grzegorz Skonieczny23, Janina Stepińska24, Agnieszka Tycińska25, Julia Maria Umińska16, Aleksander Żurakowski2627, Wacław Kochman, Wacław Kochman
DOI: 10.5603/mrj.103601

Abstract

According to the 2024 ESC guidelines for the management of chronic coronary syndrome antianginal
medical therapy aims to control symptoms while ensuring acceptable tolerability and patient adherence.
The guidelines specify the indications for particular groups of antianginal drugs, defining the class of
indications and the level of evidence based on the results of expert opinions, registries, clinical studies,
and meta-analyses. This very important document has a great impact on clinical practice as it constitutes
the basis for therapeutic decisions. Therefore, it is worth understanding the assumptions that guided the
authors when formulating specific recommendations. As the investigators of the ELCTRA -SIRIO 2 trial*,
we are monitoring new scientific evidence and new guidelines that may impact our study protocol.

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