Vol 9, No 2 (2024)
Images in medicine
Published online: 2024-06-28

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Scoliosis coexisting with autosomal dominant polycystic kidney disease

Zofia Jankowska1, Monika Gradzik2, Mariusz Niemczyk3
Medical Research Journal 2024;9(2):243-244.

Abstract

We present a case of a 49-year-old woman with autosomal dominant polycystic kidney disease and severe
scoliosis. Based on current knowledge, we think that co-occurrence of scoliosis and ADPKD is nonrandom
in our case, and we hypothesize that scoliosis should be considered a part of clinical picture of ADPKD.

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References

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  2. Peters D, Wal Av, Spruit L, et al. Cellular localization and tissue distribution of polycystin-1. Journal Pathol. 1999; 188(4): 439–446, doi: 10.1002/(sici)1096-9896(199908)188:4<439::aid-path367>3.0.co;2-p.
  3. Mangos S, Lam Py, Zhao A, et al. The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. Dis Model Mech. 2010; 3(5-6): 354–365.
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