Hybrid percutaneous atrial septal defect closure with surgical occluder fixation

Roman Przybylski1, Jędrzej Reczuch2, Maciej Bochenek1, Tomasz Witkowski2, 3, Krzysztof Reczuch2, 4, Wiktor Kuliczkowski2, 3

1Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Wroclaw Medical University, Wrocław, Poland

2Department of Heart Diseases, University Hospital, Wrocław, Poland

3Department of Cardiology, Wroclaw Medical University, Wrocław, Poland

4Department of Heart Diseases, Wroclaw Medical University, Wrocław, Poland

Correspondence to:

Jędrzej Reczuch, MD,

Department of Heart Diseases, University Hospital,

Borowska 213, 55–556 Wrocław,

phone: +48 71 736 42 57,

e-mail: jedrzej.reczuch@gmail.com

Copyright by the Author(s), 2021

Kardiol Pol. 2021; 79 (10): 1157–1158; DOI: 10.33963/KP.a2021.0078

Received: April 28, 2021

Revision accepted: July 26, 2021

Published online: July 28, 2021

A 62-year-old woman with a history of dyspnea in ordinary activities was admitted for an atrial septal defect (ASD) type 2 treatment. Transthoracic echocardiography revealed diastolic dysfunction of the left ventricle, right heart enlargement, atrial septal aneurysm, and an atrial septal defect with a left-to-right shunt. The Qp:Qs was 1.7. The probability of pulmonary hypertension was moderate. The transesophageal echocardiogram showed a 17 × 10 mm ostium secundum ASD with a left-to-right shunt, an atrial septal aneurysm protruding into the right atrium, a deficiency of the superior vena cava rim and the short aortic rim (Supplementary material, Video S1 ASD). The inferior vena cava (IVC) rim was limp. Following the European Society of Cardiology recommendations, this morphology is an indication to surgical repair; however, due to the patient’s moderate frailty, the Heart Team chose device closure instead, as it seemed technically suitable [1, 2].

The pressures in the right heart were assessed: right ventricle 27/4 mean 7 mm Hg, pulmonary artery 18/8 mean 13 mm Hg, mean wedge pressure 8 mm Hg, transpulmonary gradient 5 mm Hg, cardiac output 5.5 l/min, pulmonary vascular resistance 0.9 Wood units. After the “stop-flow” technique balloon sizing, the 20-mm “Cera” occluder was successfully placed. Despite the rim deficiency, the device was stable during the tug test. However, due to the atrial septum aneurysm, the IVC rim was loose, providing poor support for the device with a risk of detachment. The device was removed, and the concept of hybrid intervention came up.

Under general anesthesia, a lateral thoracotomy and an opening of the pericardial sac were performed. The Lifetech Cera 20-mm occluder was delivered through the right femoral vein. Both discs were expanded at optimal positions. Compression of the right atrium wall by forceps localized in transesophageal echocardiography pointed where the suture should be placed. Simultaneously, the cardiologist pulled the device to an optimized position for suturing. The right atrial disc was fixated to the limp IVC rim by a single suture placed by the surgeon through the right atrium wall (Supplementary material, Video S2device suturing). A standard tug test was performed (Supplementary material, Video S3tug test). The device had efficient support from the inferior-posterior side. The occluder was then released (Supplementary material, Video S4device detachment from delivery cable). The pericardial sac and the thoracic wall were closed. The patient was extubated the same day. Transthoracic echocardiography performed the next day showed an insignificantly small residual shunt (Supplementary material, Video S5final result). The patient was discharged after 8 days.

To the best of our knowledge, it was the first case of a hybrid percutaneous ASD closure. This unique approach allowed us to perform device closure in a patient that, due to frailty, could have had an uncertain clinical course if operated classically. This type of hybrid procedure may prove helpful in future interventions.


Supplementary material

Supplementary material is available at https://journals.viamedica.pl/kardiologia_polska.

Article information


  1. 1. Baumgartner H, De Backer J, Babu-Narayan S, et al. 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J. 2021; 42(6): 563645, doi: 10.1093/eurheartj/ehaa554, indexed in Pubmed: 32860028.
  2. 2. Grygier M, Sabiniewicz R, Smolka G, et al. Percutaneous closure of atrial septal defect: a consensus document of the joint group of experts from the Association of Cardiovascular Interventions and the Grown-Up Congenital Heart Disease Section of the Polish Cardiac Society. Kardiol Pol. 2020; 78(10): 10661083, doi: 10.33963/KP.15629, indexed in Pubmed: 33016689.


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