open access

Vol 79, No 6 (2021)
Original article
Published online: 2021-04-06
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A simplified acute kidney injury predictor following transcatheter aortic valve implantation: ACEF score

Begum Uygur, Omer Celik, Ali Riza Demir, Ahmet Anil Sahin, Ahmet Guner, Yalcin Avci, Umit Bulut, Omer Tasbulak, Gokhan Demirci, Fatih Uzun, Ali Kemal Kalkan, Mehmet Erturk
DOI: 10.33963/KP.15933
·
Pubmed: 33871229
·
Kardiol Pol 2021;79(6):662-668.

open access

Vol 79, No 6 (2021)
Original article
Published online: 2021-04-06

Abstract

Background: Transcatheter aortic valve implantation (TAVI) is an effective, less invasive treatment alternative for symptomatic severe aortic stenosis (AS). Acute kidney injury (AKI) following TAVI is a common complication and is associated with worse outcomes. The age, creatinine, ejection fraction (ACEF) score is a simple scoring method, including only three parameters: age, creatinine, and ejection fraction (EF). The score was well established in predicting AKI after coronary interventions.
Aims: We aimed to evaluate whether this simple scoring method, ACEF, may predict a development of AKI in patients who underwent TAVI.
Methods: A total of 173 consecutive patients with symptomatic severe AS who underwent TAVI were included retrospectively. The primary endpoint of the study was the development of AKI. Study population was divided into two groups according to the presence of AKI. The ACEF score was calculated with the formula: age/EF + 1 (if baseline creatinine >2 mg/dl).
Results: Twenty-nine patients developed AKI. The median (interquartile range) ACEF score was 1.36 (1.20–1.58). The ACEF score was found to be an independent predictor of AKI (P <0.001). The ACEF score ≥1.36 predicted AKI development with a sensitivity of 96.6% and specificity of 58.8%. Moreover, hypertension, hemoglobin levels, contrast volume, and aortic valve area (AVA) were found to be independent predictors of AKI.
Conclusions: Our study revealed that the ACEF score was an independent predictor of AKI. A simple and objective score might be very useful in predicting AKI development in patients undergoing TAVI.

Abstract

Background: Transcatheter aortic valve implantation (TAVI) is an effective, less invasive treatment alternative for symptomatic severe aortic stenosis (AS). Acute kidney injury (AKI) following TAVI is a common complication and is associated with worse outcomes. The age, creatinine, ejection fraction (ACEF) score is a simple scoring method, including only three parameters: age, creatinine, and ejection fraction (EF). The score was well established in predicting AKI after coronary interventions.
Aims: We aimed to evaluate whether this simple scoring method, ACEF, may predict a development of AKI in patients who underwent TAVI.
Methods: A total of 173 consecutive patients with symptomatic severe AS who underwent TAVI were included retrospectively. The primary endpoint of the study was the development of AKI. Study population was divided into two groups according to the presence of AKI. The ACEF score was calculated with the formula: age/EF + 1 (if baseline creatinine >2 mg/dl).
Results: Twenty-nine patients developed AKI. The median (interquartile range) ACEF score was 1.36 (1.20–1.58). The ACEF score was found to be an independent predictor of AKI (P <0.001). The ACEF score ≥1.36 predicted AKI development with a sensitivity of 96.6% and specificity of 58.8%. Moreover, hypertension, hemoglobin levels, contrast volume, and aortic valve area (AVA) were found to be independent predictors of AKI.
Conclusions: Our study revealed that the ACEF score was an independent predictor of AKI. A simple and objective score might be very useful in predicting AKI development in patients undergoing TAVI.

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Keywords

ACEF score, acute kidney injury, transcatheter aortic valve implantation

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About this article
Title

A simplified acute kidney injury predictor following transcatheter aortic valve implantation: ACEF score

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 79, No 6 (2021)

Article type

Original article

Pages

662-668

Published online

2021-04-06

DOI

10.33963/KP.15933

Pubmed

33871229

Bibliographic record

Kardiol Pol 2021;79(6):662-668.

Keywords

ACEF score
acute kidney injury
transcatheter aortic valve implantation

Authors

Begum Uygur
Omer Celik
Ali Riza Demir
Ahmet Anil Sahin
Ahmet Guner
Yalcin Avci
Umit Bulut
Omer Tasbulak
Gokhan Demirci
Fatih Uzun
Ali Kemal Kalkan
Mehmet Erturk

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