open access

Vol 68, No 1 (2010)
Other
Published online: 2010-02-03
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Original article
Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery – 12-month follow-up

Radosław Kręcki, Jarosław Drożdż, Piotr Szcześniak, Jarosław D. Kasprzak, Jan Z. Peruga, Piotr Lipiec, Karina Wierzbowska-Drabik, Jakub Foryś, Daria Orszulak-Michalak, Maria Krzemińska-Pakuła
Kardiol Pol 2010;68(1):22-30.

open access

Vol 68, No 1 (2010)
Other
Published online: 2010-02-03

Abstract

Background: Treatment of chronic diseases, such as atherosclerosis, usually leads to significant short-term improvement. Mid- and long-term results are not always as satisfactory. That is why improvement of quality of life should be the leading qualification criterion for invasive procedures, which sometimes carry a risk of complications.
Aim: To determine the quality of life in patients with stable, multivessel coronary artery disease (MCAD), treated surgically or medically.
Methods: The study group comprised 107 patients (pts; 80 males) suffering from MCAD, assigned to coronary artery bypass grafting (CABG) (55 pts) or to medical treatment alone (52 pts). The mean Gensini score in the whole group was 90 (66-132). To evaluate quality of life we used a Short Form-36 (SF-36) health status survey by the International Quality of Life Assessment Project.
Results: During a 12-month follow-up 9 pts died (6 pts in the medically treated group and 3 in the CABG group), all for cardiovascular reasons. Patients treated conservatively were more often hospitalised due to angina symptoms (20 vs. 5, p = 0.003). Analysis of SF-36 showed that pts treated surgically had better improvement of quality of life in comparison with medically treated patients. Significant differences were found for physical functioning, bodily pain, vitality, mental health and mental component summary.
Conclusions: This study has shown that there is a significant difference in health-related quality of life 12 months after CABG surgery and medical treatment alone in high-risk patients with MCAD. Surgical treatment decreases the number of adverse events, better attenuates of anginal and heart failure symptoms, and improvemes the quality of life, especially the mental component. Our results should encouraged selecting patients with advanced atherosclerosis for revascularisation procedures, even if there is a very high peri-procedural risk.

Abstract

Background: Treatment of chronic diseases, such as atherosclerosis, usually leads to significant short-term improvement. Mid- and long-term results are not always as satisfactory. That is why improvement of quality of life should be the leading qualification criterion for invasive procedures, which sometimes carry a risk of complications.
Aim: To determine the quality of life in patients with stable, multivessel coronary artery disease (MCAD), treated surgically or medically.
Methods: The study group comprised 107 patients (pts; 80 males) suffering from MCAD, assigned to coronary artery bypass grafting (CABG) (55 pts) or to medical treatment alone (52 pts). The mean Gensini score in the whole group was 90 (66-132). To evaluate quality of life we used a Short Form-36 (SF-36) health status survey by the International Quality of Life Assessment Project.
Results: During a 12-month follow-up 9 pts died (6 pts in the medically treated group and 3 in the CABG group), all for cardiovascular reasons. Patients treated conservatively were more often hospitalised due to angina symptoms (20 vs. 5, p = 0.003). Analysis of SF-36 showed that pts treated surgically had better improvement of quality of life in comparison with medically treated patients. Significant differences were found for physical functioning, bodily pain, vitality, mental health and mental component summary.
Conclusions: This study has shown that there is a significant difference in health-related quality of life 12 months after CABG surgery and medical treatment alone in high-risk patients with MCAD. Surgical treatment decreases the number of adverse events, better attenuates of anginal and heart failure symptoms, and improvemes the quality of life, especially the mental component. Our results should encouraged selecting patients with advanced atherosclerosis for revascularisation procedures, even if there is a very high peri-procedural risk.
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Keywords

multivessel coronary artery disease; quality of life; treatment

About this article
Title

Original article
Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery – 12-month follow-up

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 68, No 1 (2010)

Pages

22-30

Published online

2010-02-03

Bibliographic record

Kardiol Pol 2010;68(1):22-30.

Keywords

multivessel coronary artery disease
quality of life
treatment

Authors

Radosław Kręcki
Jarosław Drożdż
Piotr Szcześniak
Jarosław D. Kasprzak
Jan Z. Peruga
Piotr Lipiec
Karina Wierzbowska-Drabik
Jakub Foryś
Daria Orszulak-Michalak
Maria Krzemińska-Pakuła

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