Acquired von Willebrand syndrome associated with indolent systemic mastocytosis

Abstract

Hereby we present case report of acquired von Willebrand syndrome (AVWS) in patient with indolent systemic mastocytosis (ISM). Systemic mastocytosis may be considered as a model disease for development of AVWS. Thereinafter, pathophysiology of the disease as well as diagnostic and therapeutic approach were extensively discussed.