open access
Management of inherited thrombocytopenia. Recommendations of the Group on Hemostasis of the Polish Society of Hematology and Transfusion Medicine, 2019
open access
Abstract
Inherited thrombocytopenias (IT) comprise a highly heterogeneous group of rare haemostatic disorders which vary in terms of degree of thrombocytopenia, platelet size, pattern of inheritance and clinical course. Due to difficult diagnosis and frequently mild clinical phenotype these disorders are often underdiagnosed. The purpose of this review is to provide clinical and laboratory characteristics of the most important types of IT. The currently available therapeutic options for these conditions are also recapitulated and discussed.
Abstract
Inherited thrombocytopenias (IT) comprise a highly heterogeneous group of rare haemostatic disorders which vary in terms of degree of thrombocytopenia, platelet size, pattern of inheritance and clinical course. Due to difficult diagnosis and frequently mild clinical phenotype these disorders are often underdiagnosed. The purpose of this review is to provide clinical and laboratory characteristics of the most important types of IT. The currently available therapeutic options for these conditions are also recapitulated and discussed.
Keywords
inherited thrombocytopenias; platelets; bleeding; diagnosis; treatment
About this articleTitle
Management of inherited thrombocytopenia. Recommendations of the Group on Hemostasis of the Polish Society of Hematology and Transfusion Medicine, 2019
Journal
Journal of Transfusion Medicine
Issue
Article type
Guidelines / Expert consensus
Pages
16-28
DOI
10.5603/JTM.2020.0001
Bibliographic record
Journal of Transfusion Medicine 2020;13(1):16-28.
Keywords
inherited thrombocytopenias
platelets
bleeding
diagnosis
treatment
Authors
Krzysztof Chojnowski
Anna Klukowska
Magdalena Łętowska
Wojciech Młynarski
Andrzej Mital
Jacek Musiał
Maria Podolak-Dawidziak
Jacek Treliński
Anetta Undas
Tomasz Urasiński
Jerzy Windyga
Joanna Zdziarska
Krystyna Zawilska