Vol 69, No 1 (2018)
Case report
Published online: 2018-03-28

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Occupational lung cancer among fisherman: a triple case report

Tarik Ghailan1, Mustapha El Ftouh12
Pubmed: 29611614
IMH 2018;69(1):46-50.

Abstract

Background: The World Health Organisation places lung cancer as the leading cause of cancer mortality in the world. The fishermen are one of the most important consumers of tobacco, which remains the main risk factor for lung cancer. However, there are no epidemiological data on the role of other causes, particularly occupational ones, in genesis of this disease. The objective of our work is to expose medical and occupational data of 3 fishermen with lung cancer and discuss a possible occupational origin of their pathology.

Case presentation: This is a case report where we describe medical and occupational data of 3 fishermen working in the port of Tangier (Morocco) who have lung cancer. The first one is an ordinary fisherman, the second is a mechanic on board and the third is an ordinary fisherman but who worked 21 years ago aboard deep-sea fishing ships as a helper in the mechanic room. All fishermen were in the fifties; the third one never smoked while the other two were described as heavy smokers. All of them were exposed during their daily work to some chemicals liable to cause lung cancer. The anatomopathological types found were 2 cases of adenocarcinoma which is the histopathological variant often found in cases of occupational origin and one case of squamous cell carcinoma.

Conclusions: The results obtained after studying these 3 cases suggest the possibility of occupational origin in the genesis of lung cancer among fishermen; however, the increased smoking rate in this population remains the most probable factor and helps the preventive approach to be adopted. More detailed epidemiological studies would highlight the possible role of occupational causes in the carcinogenesis of this pathology.  

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References

  1. WHO (World Health Organization). World Cancer Report 2008. Lyon: IARC Press; 2008.
  2. Alberg AJ, Ford JG, Samet JM, et al. American College of Chest Physicians. Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 2007; 132(3 Suppl): 29S–55S.
  3. IARC (International Agency for Research on Cancer) Working Group on the Evaluation of Carcinogenic Risks to Humans. Tobacco Smoke and involuntary Smoking. IARC Monogr Eval Carcinog Risks Hum. Vol 83. Lyon; 2004.
  4. López-Cima MF, García-Pérez J, Pérez-Gómez B, et al. Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study. Int J Health Geogr. 2011; 10: 10.
  5. Menvielle G, Boshuizen H, Kunst AE, et al. The role of smoking and diet in explaining educational inequalities in lung cancer incidence. J Natl Cancer Inst. 2009; 101(5): 321–330.
  6. Ghailan T, Hamdouch I, Bennouna A, et al. Troubles de la vigilance chez les pêcheurs de Tanger. Med Marit. 2009; 9(2).
  7. Andersen A, Barlow L, Engeland A, et al. Work-related cancer in the Nordic countries. Scand J Work Environ Health. 1994; 25(Suppl 2): 1–116.
  8. Ghailan T, Belhaje M, Aoudi YEl, et al. Évaluation du cannabisme chez les gens de Mer au nord du Maroc. Arch Mal Prof Env. 2012; 73(3): 499.
  9. Nogueroles Alonso de la Sierra P, Juan Agüera S, Almenara Barrios J, et al. [The tobacco habit among fishermen of the Barbate coast (Cádiz)]. Rev Sanid Hig Publica (Madr). 1992; 66(5-6): 299–305.
  10. Mastrangelo G, Malusa E, Veronese C, et al. Mortality from lung cancer and other diseases related to smoking among fishermen in north east Italy. Occup Environ Med. 1995; 52(3): 150–153.
  11. Sasco AJ, Merrill RM, Dari I, et al. A case-control study of lung cancer in Casablanca, Morocco. Cancer Causes Control. 2002; 13(7): 609–616.
  12. Moen BE, Nilsson R, Nordlinder R, et al. Assessment of exposure to polycyclic aromatic hydrocarbons in engine rooms by measurement of urinary 1-hydroxypyrene. Occup Environ Med. 1996; 53(10): 692–696.
  13. Steenland K, Deddens J, Stayner L. Diesel exhaust and lung cancer in the trucking industry: exposure-response analyses and risk assessment. Am J Ind Med. 1998; 34(3): 220–228, doi: 10.1002/(sici)1097-0274(199809)34:3<220::aid-ajim3>3.0.co;2-z.
  14. Lee KH, Ichiba M, Zhang J, et al. Multiple biomarkers study in painters in a shipyard in Korea. Mutat Res. 2003; 540(1): 89–98.
  15. Hammond EC, Selikoff IJ, Seidman H. Asbestos exposure, cigarette smoking and death rates. Ann N Y Acad Sci. 1979; 330: 473–490.
  16. Emmelin A, Nyström L, Wall S. Diesel exhaust exposure and smoking: a case-referent study of lung cancer among Swedish dock workers. Epidemiology. 1993; 4(3): 237–244.
  17. Yang J, Zhang H, Zhang H, et al. Smoking modify the effects of polycyclic aromatic hydrocarbons exposure on oxidative damage to DNA in coke oven workers. Int Arch Occup Environ Health. 2017; 90(5): 423–431.
  18. Ghailan T, Estopá H, Alcolea RM, et al. Comparative study of lifestyles and some unhealthy habits in coastal fishermen of the Tangier region coast (Morocco) and the coast of Catalonia (Spain). Arch Mal Prof. 2013; 74(5): 557–558.
  19. Menvielle G, Boshuizen H, Kunst AE, et al. The role of smoking and diet in explaining educational inequalities in lung cancer incidence. J Natl Cancer Inst. 2009; 101(5): 321–330.
  20. Nkosi TM, Parent MÉ, Siemiatycki J, et al. Socioeconomic position and lung cancer risk: how important is the modeling of smoking? Epidemiology. 2012; 23(3): 377–385.
  21. Heikkilä K, Nyberg ST, Theorell T, et al. IPD-Work Consortium. Work stress and risk of cancer: meta-analysis of 5700 incident cancer events in 116,000 European men and women. BMJ. 2013; 346: f165.
  22. Laraqui O, Laraqui S, Caubet A, et al. Evaluation du stress professionnel chez les gens de mer à Tanger. Med Marit. 2010; 10(1): 38–58.
  23. Samet JM, Avila-Tang E, Boffetta P, et al. Lung cancer in never smokers: clinical epidemiology and environmental risk factors. Clin Cancer Res. 2009; 15(18): 5626–5645.
  24. Luce D, Stücker I. ICARE Study Group. Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case-control study in France. BMC Public Health. 2011; 11(1): 928.