Vol 11, No 2 (2020)
Case report
Published online: 2020-07-20
Venetoclax monotherapy before second allogeneic hematopoietic stem cell transplantation in chronic lymphocytic leukemia
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Hematologia 2020;11(2):95-100.
Abstract
Chronic lymphocytic leukemia (CLL) is the most common diagnosed leukemia in adults. Its clinical course is very heterogenous and only allogeneic hematopoietic stem cell transplantation (allo-HSCT) ensures cure of this disease. Introduction of venetoclax, an antagonist of the antiapoptotic BCL-2 protein, significantly improved patient outcome. Herein we present the use of venetoclax monotherapy as a bridging therapy before second allo-HSCT in a patient with relapsed and refractory CLL.
Keywords: venetoclaxchronic lymphocytic leukemiaallogeneic hematopoietic stem cell transplantation
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