The efficacy of treatment with ruxolitinib in a patient with secondary post polycythemia vera mielofibrosis with thrombosis in portal circulation

Abstract

Management of mielofibrosis remain still as open task, especially in case of disease lasting many years and complicated by thrombosis in portal vein. The history of treatment started from 1996, and is a good example for adjusting various treatment methods for existing possibilities and patient needs. Therapy using ruxolitinib caused clinical improvement, decrease of portal hypertension symptoms with clinical stability and circulation improvement.