Vol 9, No 2 (2018)
Case report
Published online: 2018-08-17
Renal cell carcinoma in patients with multiple myeloma – 2 case reports and review of literature
Hematologia 2018;9(2):153-159.
Abstract
Multiple myeloma (MM) is characterized by malignant spreading of monoclonal plasma cells in bone marrow. Renal cell carcinoma (RCC) is a result of neoplastic proliferation of epithelial cells in nephron proximal convoluted tubule and forms 95% of malignant kidney’s neoplasms. There are some reports about coexistence of MM and RCC but it is a rare phenomenon. We describe two cases of patients in which during the therapy of MM, RCC was detected accidentally. Radical nephrectomy in early stage of RCC allowed complete recovery and did not interrupt the continuation of MM’s therapy. Additionally, similar cases from literature are discussed.
Keywords: myeloma multiplerenal cell carcinomacoexistence of neoplasmsinterleukin 6lenalidomide.
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