open access

Vol 8, No 2 (2017)
Case report
Published online: 2017-09-06
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Coexistence of plasma cell dyscrasias and myelodysplastic syndrome — study of cases and review of literature

Aleksandra Gołos1, Anna Paczek1, Ewa Lech-Marańda12, Krzysztof Warzocha1, Joanna Góra-Tybor1
DOI: 10.5603/Hem.2017.0017
·
Hematologia 2017;8(2):144-151.
Affiliations
  1. Klinika Hematologii, Instytut Hematologii i Transfuzjologii, ul. Indiry Gandhi 14, 02–776 Warszawa, Poland
  2. Klinika Hematologii i Transfuzjologii, Centrum Medyczne Kształcenia Podyplomowego, ul. Indiry Gandhi 14, 02–776 Warszawa, Poland

open access

Vol 8, No 2 (2017)
CASE REPORTS
Published online: 2017-09-06

Abstract

The improvement in plasma cell myeloma (PCM) treatment and much longer overall survival of the patients led to the observation of long-term complications of the therapy. These include secondary malignancies, such as myelodysplastic syndromes (MDS) and acute myeloid leukemia. Definitely less common is the co-occurrence of MDS at the point of diagnosis of PCM or MDS evolving during the observation of untreated patients with monoclonal gammapathy of undetermined significance. In the article we describe 5 patients: one with a therapy-related MDS, the co-occurrence of both diseases from the diagnosis and MDS preceding PCM for several years.

Abstract

The improvement in plasma cell myeloma (PCM) treatment and much longer overall survival of the patients led to the observation of long-term complications of the therapy. These include secondary malignancies, such as myelodysplastic syndromes (MDS) and acute myeloid leukemia. Definitely less common is the co-occurrence of MDS at the point of diagnosis of PCM or MDS evolving during the observation of untreated patients with monoclonal gammapathy of undetermined significance. In the article we describe 5 patients: one with a therapy-related MDS, the co-occurrence of both diseases from the diagnosis and MDS preceding PCM for several years.

Get Citation

Keywords

plasma cell myeloma, acute myeloid leukemia, myelodysplastic syndrome

About this article
Title

Coexistence of plasma cell dyscrasias and myelodysplastic syndrome — study of cases and review of literature

Journal

Hematology in Clinical Practice

Issue

Vol 8, No 2 (2017)

Article type

Case report

Pages

144-151

Published online

2017-09-06

DOI

10.5603/Hem.2017.0017

Bibliographic record

Hematologia 2017;8(2):144-151.

Keywords

plasma cell myeloma
acute myeloid leukemia
myelodysplastic syndrome

Authors

Aleksandra Gołos
Anna Paczek
Ewa Lech-Marańda
Krzysztof Warzocha
Joanna Góra-Tybor

References (31)
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