Vol 4, No 2 (2013)
Review paper
Published online: 2013-06-25

open access

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Diffuse large B-cell lymphoma — management recommendations of the Institute of Hematology and Transfusion Medicine

Krzysztof Warzocha
Hematologia 2013;4(2):123-136.


Diffuse large B-cell lymphoma (DLBCL) is a group of lymphoid malignancies derived from mature
peripheral B lymphocytes arising in germinal centres. It is the most commonly occurring of
all lymphoma types (appr. 30%) and aggressive subtypes (appr. 80%). Its heterogeneity serve as the
basis for DLBCL classification into clinical, morphological, molecular and immunohistochemical
subtypes. To achieve optimal use of all available diagnostic and therapeutic resources in DLBCL
patient management, the Institute of Hematology and Transfusion Medicine has developed and
implemented a set of internal recommendations. As in previous publications of this kind, these
recommendations refer mostly to clinical practice. For further details please consult; http://www.

Hematology in Clinical Practice