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Juvenile granulosa cell tumor: 20 years’ experience of a Tertiary Center
, 1, 2, 3, 1, 3
Affiliations- Department of Obstetrics and Gynecology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
- Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
- Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
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Abstract
Objectives: The aim of this study is to share of the 20-year experience of a tertiary center about juvenile granulosa cell tumor (JGCT) and describe clinic manifestations, treatment, and outcome of patients who diagnosed JGCT.
Material and methods: Five patients who diagnosed juvenile granulosa cell tumor between 2000 and 2020 were included in the study. The demographics, clinical findings and outcomes were retrospectively evaluated. Of the 5 patients
in our study, one was in the premenarcheal girl. The common complaint in all of our patients was abdominal swelling. In preoperative imaging methods, all patients had unilateral adnexal mass and no signs in favor of metastasis. All patients were staged according to FIGO classification for ovarian tumors; 3 of patients had stage IA disease, one of patients had stage IC1 and one of patients had stage IC2. All patients underwent different surgecal procedures which is appropriate for their clinical manifestations. In addition to surgery 2 patients received adjuvant chemotherapy.
Results: The median follow-up period of the patients was 60 mounts and recurrence was observed in two patients who
were reoperated. We have no patients who died due to this disease.
Conclusions: Possible diagnosis of juvenile granulosa cell tumor should be kept in mind in a patient of young age with unilateral adnexal mass with benign features.
Abstract
Objectives: The aim of this study is to share of the 20-year experience of a tertiary center about juvenile granulosa cell tumor (JGCT) and describe clinic manifestations, treatment, and outcome of patients who diagnosed JGCT.
Material and methods: Five patients who diagnosed juvenile granulosa cell tumor between 2000 and 2020 were included in the study. The demographics, clinical findings and outcomes were retrospectively evaluated. Of the 5 patients
in our study, one was in the premenarcheal girl. The common complaint in all of our patients was abdominal swelling. In preoperative imaging methods, all patients had unilateral adnexal mass and no signs in favor of metastasis. All patients were staged according to FIGO classification for ovarian tumors; 3 of patients had stage IA disease, one of patients had stage IC1 and one of patients had stage IC2. All patients underwent different surgecal procedures which is appropriate for their clinical manifestations. In addition to surgery 2 patients received adjuvant chemotherapy.
Results: The median follow-up period of the patients was 60 mounts and recurrence was observed in two patients who
were reoperated. We have no patients who died due to this disease.
Conclusions: Possible diagnosis of juvenile granulosa cell tumor should be kept in mind in a patient of young age with unilateral adnexal mass with benign features.
Keywords
juvenile granulosa cell tumours; ovarian malignancy; sex cord–stromal tumours, pathology
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About this articleTitle
Juvenile granulosa cell tumor: 20 years’ experience of a Tertiary Center
Journal
Issue
Article type
Research paper
Pages
787-792
Published online
2022-10-12
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3846
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1261
DOI
Pubmed
Bibliographic record
Ginekol Pol 2022;93(10):787-792.
Keywords
juvenile granulosa cell tumours
ovarian malignancy
sex cord–stromal tumours
pathology
Authors
Kübra Hamzaoğlu Canbolat
Elifnur Biçer
Şennur İlvan
Tugan Beşe
İsmail Çepni
Fuat Demirkıran
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