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Severe course of COVID-19 in pregnant woman and newborn’s alloimmune thrombocytopenia — case study and review of the literature
, 1, 1, 2, 3, 4, 15
Affiliations- Department of Obstetrics and Gynecology, Central Clinical Hospital of the Ministry of the Interior and Administration (MSWiA), Warsaw, Poland
- Department of Neonatology, Central Clinical Hospital of the Ministry of the Interior and Administration (MSWiA), Warsaw, Poland
- Department of Anaesthesiology and Intensive Therapy, Central Clinical Hospital of the Ministry of the Interior and Administration (MSWiA), Warsaw, Poland
- University of Humanities and Economics, Lodz, Satellite Campus in Warsaw, Poland
- Center of Reproductive Health, Institute of Mother and Child, Warsaw, Poland
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Abstract
So far, little is known about the impact of the coronavirus disease 2019 (COVID-19) on pregnancy and data is often inconsistent. Even less information has been published on the management of severe courses of COVID-19 in pregnant women. By writing this article, we aim to share our experience in the treatment of pregnant woman critically ill with COVID-19 and newborn’s condition, fetal and neonatal alloimmune thrombocytopenia (FNAIT), as well as literature review of this disease. After admission, the woman’s respiratory status rapidly worsened, requiring administration of oxygen and in the end ECMO therapy. At the 9th day of ECMO support, and 28 weeks 3 days of gestation, due to mother’s prognosis and increased feto-placental vascular resistance a decision of Caesarean section was taken. The neonate required intensive care not only due to extreme prematurity but coagulation disorder, alloimmune thrombocytopenia, which we diagnosed a few weeks after delivery.
Abstract
So far, little is known about the impact of the coronavirus disease 2019 (COVID-19) on pregnancy and data is often inconsistent. Even less information has been published on the management of severe courses of COVID-19 in pregnant women. By writing this article, we aim to share our experience in the treatment of pregnant woman critically ill with COVID-19 and newborn’s condition, fetal and neonatal alloimmune thrombocytopenia (FNAIT), as well as literature review of this disease. After admission, the woman’s respiratory status rapidly worsened, requiring administration of oxygen and in the end ECMO therapy. At the 9th day of ECMO support, and 28 weeks 3 days of gestation, due to mother’s prognosis and increased feto-placental vascular resistance a decision of Caesarean section was taken. The neonate required intensive care not only due to extreme prematurity but coagulation disorder, alloimmune thrombocytopenia, which we diagnosed a few weeks after delivery.
Keywords
pregnancy; COVID-19; ECMO; FNAIT
About this articleTitle
Severe course of COVID-19 in pregnant woman and newborn’s alloimmune thrombocytopenia — case study and review of the literature
Journal
Issue
Article type
Review paper
Pages
565-569
Published online
2022-09-21
Page views
1214
Article views/downloads
430
DOI
Pubmed
Bibliographic record
Ginekol Pol 2023;94(7):565-569.
Keywords
pregnancy
COVID-19
ECMO
FNAIT
Authors
Angelika Piotrowska-Gwizdak
Karolina Krajewska
Hanna Blaszczyk
Anna Gluszko
Konstanty Szuldrzynski
Waldemar Wierzba
Artur J. Jakimiuk
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