open access

Vol 93, No 1 (2022)
Research paper
Published online: 2022-01-15
Get Citation

COVID-19 in pregnancy, management and outcomes among pregnant women and neonates — results from tertiary care center in Wroclaw

Paulina Szczygiol1, Karolina Baranska1, Ilona Korczak1, Aleksandra Zimmer-Stelmach2, Anna Rosner-Tenerowicz2, Mariusz Zimmer2, Barbara Krolak-Olejnik1
·
Pubmed: 35072251
·
Ginekol Pol 2022;93(1):47-53.
Affiliations
  1. Department and Clinic of Neonatology Wroclaw Medical University, Poland, Poland
  2. 2nd Department and Clinic of Gynecology and Obstetrics Wroclaw Medical University, Poland, Poland

open access

Vol 93, No 1 (2022)
ORIGINAL PAPERS Obstetrics
Published online: 2022-01-15

Abstract

Objectives: A novel coronavirus — SARS CoV-2 — outbreak has, for sure, been the greatest medical challenge in recent years. The maternal and neonatal consequences of the infection are still largely unknown. Material and methods: This prospective study aims to describe the perinatal care and outcomes of SARS-CoV-2 positive pregnant women and their newborn infants during the third wave of the pandemic, in a large tertiary university center in Wroclaw/Poland from 15 February to 1 May 2021. Results: The paper describes a group of 83 women with confirmed SARS-CoV-2 infection during delivery, as well as their newborn infants (n = 84). The course of COVID-19 disease in pregnant patients was mostly asymptomatic (56%) but 31% women manifested mild to moderate symptoms and 14% had severe infection. The median gestational age at the delivery was 38 weeks. On average, 16.7% of mothers were separated from their newborns at birth, 83.3% practiced skin-to-skin, and roomed in with their babies, and 84.5% of the infants received any mother’s milk.  Preterm infants were more often borne by mothers with symptomatic course of COVID-19 infection. Need for neonatal treatment was only due to prematurity. Neonates with acquired infection (after 14th day of life) had to be treated symptomatically with fever and loose stools, only 28.5% had symptoms of respiratory failure. Conclusions:  Despite the confirmed SARS-CoV-2 infection, the majority of mother- infant dyads were in a good health condition. The data on perinatal care reported in the paper could be helpful contribution supporting childbirth physiology protection during the COVID-19 pandemic.

Abstract

Objectives: A novel coronavirus — SARS CoV-2 — outbreak has, for sure, been the greatest medical challenge in recent years. The maternal and neonatal consequences of the infection are still largely unknown. Material and methods: This prospective study aims to describe the perinatal care and outcomes of SARS-CoV-2 positive pregnant women and their newborn infants during the third wave of the pandemic, in a large tertiary university center in Wroclaw/Poland from 15 February to 1 May 2021. Results: The paper describes a group of 83 women with confirmed SARS-CoV-2 infection during delivery, as well as their newborn infants (n = 84). The course of COVID-19 disease in pregnant patients was mostly asymptomatic (56%) but 31% women manifested mild to moderate symptoms and 14% had severe infection. The median gestational age at the delivery was 38 weeks. On average, 16.7% of mothers were separated from their newborns at birth, 83.3% practiced skin-to-skin, and roomed in with their babies, and 84.5% of the infants received any mother’s milk.  Preterm infants were more often borne by mothers with symptomatic course of COVID-19 infection. Need for neonatal treatment was only due to prematurity. Neonates with acquired infection (after 14th day of life) had to be treated symptomatically with fever and loose stools, only 28.5% had symptoms of respiratory failure. Conclusions:  Despite the confirmed SARS-CoV-2 infection, the majority of mother- infant dyads were in a good health condition. The data on perinatal care reported in the paper could be helpful contribution supporting childbirth physiology protection during the COVID-19 pandemic.

Get Citation

Keywords

COVID-19; perinatal care; SARS-CoV-2; neonate; pregnancy outcomes

About this article
Title

COVID-19 in pregnancy, management and outcomes among pregnant women and neonates — results from tertiary care center in Wroclaw

Journal

Ginekologia Polska

Issue

Vol 93, No 1 (2022)

Article type

Research paper

Pages

47-53

Published online

2022-01-15

Page views

6366

Article views/downloads

790

DOI

10.5603/GP.a2021.0201

Pubmed

35072251

Bibliographic record

Ginekol Pol 2022;93(1):47-53.

Keywords

COVID-19
perinatal care
SARS-CoV-2
neonate
pregnancy outcomes

Authors

Paulina Szczygiol
Karolina Baranska
Ilona Korczak
Aleksandra Zimmer-Stelmach
Anna Rosner-Tenerowicz
Mariusz Zimmer
Barbara Krolak-Olejnik

References (23)
  1. Mark EG, McAleese S, Golden WC, et al. Coronavirus Disease 2019 in Pregnancy and Outcomes Among Pregnant Women and Neonates: A Literature Review. Pediatr Infect Dis J. 2021; 40(5): 473–478.
  2. Wang S, Guo L, Chen L, et al. A Case Report of Neonatal 2019 Coronavirus Disease in China. Clin Infect Dis. 2020; 71(15): 853–857.
  3. Chen D, Yang H, Cao Y, et al. Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection. Int J Gynaecol Obstet. 2020; 149(2): 130–136.
  4. Royal College of Obstetricians and Gynaecologists (RCOG). The Grants Register 2021. 2020: 713–721.
  5. Bohren MA, Berger BO, Munthe-Kaas H, et al. Perceptions and experiences of labour companionship: a qualitative evidence synthesis. Cochrane Database Syst Rev. 2019; 3: CD012449.
  6. Williams J, Namazova-Baranova L, Weber M, et al. The Importance of Continuing Breastfeeding during Coronavirus Disease-2019: In Support of the World Health Organization Statement on Breastfeeding during the Pandemic. The Journal of Pediatrics. 2020; 223: 234–236.
  7. Vassilopoulou E, Feketea G, Koumbi L, et al. Breastfeeding and COVID-19: From Nutrition to Immunity. Frontiers in Immunology. 2021; 12.
  8. Rekomendowana ścieżka postępowania dla kobiet w ciąży COVID-19. https://www.ptgin.pl/rekomendowana-sciezka-postepowania-dla-kobiet-w-ciazy-covid-19.
  9. Zalecenia Polskiego Towarzystwa Neonatologicznego Krajowego Nadzoru w dziedzinie neonatologii. (2020) Postępowanie z noworodkiem przy podejrzeniu/potwierdzeniu zakażenia SARS-CoV-2 u matki oraz z rozpoznaniem zakażenia SARS-CoV-2. http://www.neonatologia.edu.pl/index.php?option=com_content&view=article&id=215:postepowanie-z-noworodkiem-przy-podejrzeniu-potwierdzeniu-zakazenia-sars-cov-2-u-matki-oraz-z-rozpoznaniem-zakazenia-sars-cov-2&catid=8&Itemid=103.
  10. Reale SC, Lumbreras-Marquez MI, King CH, et al. Patient characteristics associated with SARS-CoV-2 infection in parturients admitted for labour and delivery in Massachusetts during the spring 2020 surge: A prospective cohort study. Paediatr Perinat Epidemiol. 2021; 35(1): 24–33.
  11. Allotey J, Stallings E, Bonet M, et al. for PregCOV-19 Living Systematic Review Consortium. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ. 2020; 370: m3320.
  12. Public Health England. COVID-19: investigation and initial clinical management of possible cases 2020. https://www.gov.uk/government/publications/wuhan-novel-coronavirus-initialinvestigation-of-possible-cases/investigation-and-initial-clinical-management-of-possible-casesof-wuhan-novel-coronavirus-wn-cov-infection.
  13. Vouga M, Favre G, Perez OM, et al. Maternal and Obstetrical Outcomes in a Cohort of Pregnant Women Tested for SARS-CoV-2: Interim Results of the COVI-Preg International Registry. SSRN Electronic Journal. .
  14. Zimmermann P, Curtis N, Zimmermann P, et al. Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children. Pediatr Infect Dis J. 2020; 39(5): 355–368.
  15. Donati S, Corsi E, Salvatore MA, et al. Childbirth Care among SARS-CoV-2 Positive Women in Italy. Int J Environ Res Public Health. 2021; 18(8).
  16. Cardona-Pérez J, Villegas-Mota I, Helguera-Repetto A, et al. Prevalence, clinical features, and outcomes of SARS-CoV-2 infection in pregnant women with or without mild/moderate symptoms: Results from universal screening in a tertiary care center in Mexico City, Mexico. PLOS ONE. 2021; 16(4): e0249584.
  17. Ciapponi A, Bardach A, Comandé D, et al. COVID-19 and pregnancy: An umbrella review of clinical presentation, vertical transmission, and maternal and perinatal outcomes. PLoS One. 2021; 16(6): e0253974.
  18. Jering KS, Claggett BL, Cunningham JW, et al. Clinical Characteristics and Outcomes of Hospitalized Women Giving Birth With and Without COVID-19. JAMA Intern Med. 2021; 181(5): 714–717.
  19. Lokken E, Huebner E, Taylor G, et al. Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State. American Journal of Obstetrics and Gynecology. 2021; 225(1): 77.e1–77.e14.
  20. Nayak M, Panda S, Panda S, et al. Neonatal outcomes of pregnant women with COVID-19 in a developing country setup. Pediatrics & Neonatology. 2021; 62(5): 499–505.
  21. Chen Y, Peng H, Wang L, et al. Infants Born to Mothers With a New Coronavirus (COVID-19). Front Pediatr. 2020; 8: 104.
  22. Angelidou A, Sullivan K, Melvin P, et al. Association of Maternal Perinatal SARS-CoV-2 Infection With Neonatal Outcomes During the COVID-19 Pandemic in Massachusetts. JAMA Network Open. 2021; 4(4): e217523.
  23. Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational Pediatrics. 2020; 9(1): 51–60.

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Group sp. z o.o., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl