Vol 92, No 8 (2021)
Research paper
Published online: 2021-04-08

open access

Page views 1360
Article views/downloads 1048
Get Citation

Connect on Social Media

Connect on Social Media

Pregnancy related and postpartum admissions to intensive care unit in the obstetric tertiary care center — an 8-year retrospective study

Pawel Krawczyk1, Agnieszka Jastrzebska1, Daniel Lipka2, Hubert Huras2
Pubmed: 33844261
Ginekol Pol 2021;92(8):575-578.

Abstract

Objectives: The purpose of the study was to analyze the incidence of maternal morbidity and mortality of pregnant and postpartum women admitted to the intensive care unit (ICU).
Material and methods: Retrospective analysis of all pregnant and postpartum patients admitted to ICU of the obstetric tertiary care center between January 1, 2007 and December 31, 2014.
Results: A total of 266 patients with pregnancy and postpartum related morbidity were admitted to ICU (12.56 per 1000 deliveries). It accounted for 21.08% of all adult admissions of the unit. Mean age was 30.2 ± 5.6 years, mean gestational age was 30.8 ± 7.6 weeks. Two hundred forty patients (90.23%) were primiparous, 17 (6.4%) were twin pregnancy. Main reasons of admission included hypertensive disorders of pregnancy n = 99 (37.22%; 4.68 per 1000 deliveries), hemorrhage n = 46 (17.29%; 2.17 per 1000 deliveries) and sepsis/infection n = 46 (17.29%; 2.17 per 1000 deliveries). Median length of stay was five days (IQR 4–7). Artificial ventilation was required in 91 patients (34.21%), 147 (55.26%) required vasoactive drugs, 33 (12.41%) had metabolic disturbances, 21 (7.89%) required total parenteral nutrition and 4 (1.50%) renal replacement therapy. We report four maternal deaths (1.5%; 0.19 per 1000 deliveries).
Conclusions: There are three main reasons of obstetric ICU admissions: hypertensive disorders of pregnancy, obstetric hemorrhage and sepsis/infection. The majority of obstetric patients admitted to ICU did not require multi-organ supportive therapy. Availability of intermediate care facility could reduce unnecessary admission to ICU.

Article available in PDF format

View PDF Download PDF file

References

  1. MBRRACE-UK - Saving Lives, Improving Mothers’ Care 2019. https://www.npeu.ox.ac.uk/assets/downloads/mbrrace-uk/reports/MBRRACE-UK%20Maternal%20Report%202019%20-%20WEB%20VERSION.pdf (27.09.2020).
  2. Einav S, Leone M. Epidemiology of obstetric critical illness. Int J Obstet Anesth. 2019; 40: 128–139.
  3. Ludność w województwie Małopolskim. Urodzenia w województwie Małopolskim. https://krakow.stat.gov.pl/ (27.09.2020).
  4. R Core Team. A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/ (27.09.2020).
  5. Pollock W, Rose L, Dennis CL. Pregnant and postpartum admissions to the intensive care unit: a systematic review. Intensive Care Med. 2010; 36(9): 1465–1474.
  6. Chantry AA, Deneux-Tharaux C, Bonnet MP, et al. Pregnancy-related ICU admissions in France: trends in rate and severity, 2006-2009. Crit Care Med. 2015; 43(1): 78–86.
  7. Oud L. Epidemiology of Pregnancy-Associated ICU Utilization in Texas: 2001 - 2010. J Clin Med Res. 2017; 9(2): 143–153.
  8. Zwart JJ, Dupuis JRO, Richters A, et al. Obstetric intensive care unit admission: a 2-year nationwide population-based cohort study. Intensive Care Med. 2010; 36(2): 256–263.
  9. Wanderer JP, Leffert LR, Mhyre JM, et al. Epidemiology of obstetric-related ICU admissions in Maryland: 1999-2008*. Crit Care Med. 2013; 41(8): 1844–1852.
  10. Mirghani HM, Hamed M, Ezimokhai M, et al. Pregnancy-related admissions to the intensive care unit. Int J Obstet Anesth. 2004; 13(2): 82–85.
  11. Keizer JL, Zwart JJ, Meerman RH, et al. Obstetric intensive care admissions: a 12-year review in a tertiary care centre. Eur J Obstet Gynecol Reprod Biol. 2006; 128(1-2): 152–156.
  12. Female admissions (aged 16–50 years) to adult, general critical care units in England, Wales and Northern Ireland reported as ‘currently pregnant’ or ‘recently pregnant’. 1 January 2009 to 31 December 2012. https://www.oaa-anaes.ac.uk/assets/_managed/cms/files/Obstetric%20admissions%20to%20critical%20care%202009-2012%20-%20FINAL.pdf (27.09.2020).
  13. Lazariu V, Nguyen T, McNutt LA, et al. Severe maternal morbidity: A population-based study of an expanded measure and associated factors. PLoS One. 2017; 12(8): e0182343.
  14. Leovic MP, Robbins HN, Starikov RS, et al. Multidisciplinary obstetric critical care delivery: The concept of the "virtual" intensive care unit. Semin Perinatol. 2018; 42(1): 3–8.
  15. Demirkiran O, Dikmen Y, Utku T, et al. Critically ill obstetric patients in the intensive care unit. Int J Obstet Anesth. 2003; 12(4): 266–270.
  16. Swartz RH, Cayley ML, Foley N, et al. The incidence of pregnancy-related stroke: A systematic review and meta-analysis. Int J Stroke. 2017; 12(7): 687–697.
  17. Oud L, Watkins P. Evolving trends in the epidemiology, resource utilization, and outcomes of pregnancy-associated severe sepsis: a population-based cohort study. J Clin Med Res. 2015; 7(6): 400–416.
  18. Acosta CD, Kurinczuk JJ, Lucas DN, et al. United Kingdom Obstetric Surveillance System. Severe maternal sepsis in the UK, 2011-2012: a national case-control study. PLoS Med. 2014; 11(7): e1001672.
  19. Chantry AA, Deneux-Tharaux C, Cans C, et al. GRACE study group. Hospital discharge data can be used for monitoring procedures and intensive care related to severe maternal morbidity. J Clin Epidemiol. 2011; 64(9): 1014–1022.
  20. Dennis AT, Solnordal CB. Acute pulmonary oedema in pregnant women. Anaesthesia. 2012; 67(6): 646–659.
  21. Maternal mortality: Levels and trends 2000 to 2017 Authors: WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division. https://www.who.int/reproductivehealth/publications/maternal-mortality-2000-2017/en/ (27.09.2020).