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Research paper
Published online: 2021-08-06
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Mother and neonate suffering from COVID-19 infection. Is there any risk of vertical transmission? A case report

Agnieszka Urban1, Michal Dyrda1
DOI: 10.5603/GP.a2021.0033
·
Pubmed: 34541649


Affiliations

  1. Department of Gynaecology and Obstetrics Regional Specialist Hospital Megrez in Tychy, Poland

open access

Ahead of Print
ORIGINAL PAPERS Obstetrics
Published online: 2021-08-06

Abstract

Objectives: This study was carried out to visualize possible infection of the fetus during pregnancy through vertical
transmission.
Material and methods: A descriptive observational study was conducted on a 39th week pregnant woman who was
suspected COVID-19. Pregnancy was ended with a caesarean section due to epidemiological reasons. The mother and
newborn were examined for COVID-19 infection using PCR swabs.
Results: At first there were discrepancies between SARS-CoV-2 test results from the nasopharyngeal swabs of the mother
and the neonate. The mother tested positive, whereas the newborn tested negative. However, neonate’s control swab was
repeated within the following 48 hours and revealed a positive test result.
Conclusions: The risk of vertical transmission with SARS-COV2 is possible, therefore it is very important to isolate pregnant
women from infected people to protect mothers and newborns.

Abstract

Objectives: This study was carried out to visualize possible infection of the fetus during pregnancy through vertical
transmission.
Material and methods: A descriptive observational study was conducted on a 39th week pregnant woman who was
suspected COVID-19. Pregnancy was ended with a caesarean section due to epidemiological reasons. The mother and
newborn were examined for COVID-19 infection using PCR swabs.
Results: At first there were discrepancies between SARS-CoV-2 test results from the nasopharyngeal swabs of the mother
and the neonate. The mother tested positive, whereas the newborn tested negative. However, neonate’s control swab was
repeated within the following 48 hours and revealed a positive test result.
Conclusions: The risk of vertical transmission with SARS-COV2 is possible, therefore it is very important to isolate pregnant
women from infected people to protect mothers and newborns.

Get Citation

Keywords

COVID-19; SARS-CoV-2; vertical transmission; coronavirus; neonate

About this article
Title

Mother and neonate suffering from COVID-19 infection. Is there any risk of vertical transmission? A case report

Journal

Ginekologia Polska

Issue

Ahead of Print

Article type

Research paper

Published online

2021-08-06

DOI

10.5603/GP.a2021.0033

Pubmed

34541649

Keywords

COVID-19
SARS-CoV-2
vertical transmission
coronavirus
neonate

Authors

Agnieszka Urban
Michal Dyrda

References (11)
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  2. Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet. 2020; 395(10226): 809–815.
  3. Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). Indian J Pediatr. 2020; 87(4): 281–286.
  4. Qiao J. What are the risks of COVID-19 infection in pregnant women? The Lancet. 2020; 395(10226): 760–762.
  5. Alzamora MC, Paredes T, Caceres D, et al. Severe COVID-19 during Pregnancy and Possible Vertical Transmission. Am J Perinatol. 2020; 37(8): 861–865.
  6. Iqbal SN, Overcash R, Mokhtari N, et al. An Uncomplicated Delivery in a Patient with Covid-19 in the United States. N Engl J Med. 2020; 382(16): e34.
  7. Davanzo R, Moro G, Sandri F, et al. Breastfeeding and coronavirus disease-2019: Ad interim indications of the Italian Society of Neonatology endorsed by the Union of European Neonatal & Perinatal Societies. Matern Child Nutr. 2020; 16(3): e13010.
  8. Yang Pu, Wang X, Liu P, et al. Clinical characteristics and risk assessment of newborns born to mothers with COVID-19. J Clin Virol. 2020; 127: 104356.
  9. Delfino M, Guida M, Patrì A, et al. SARS-CoV-2 possible contamination of genital area: implications for sexual and vertical transmission routes. J Eur Acad Dermatol Venereol. 2020; 34(8): e364–e365.
  10. Winichakoon P, Chaiwarith R, Liwsrisakun C, et al. Negative Nasopharyngeal and Oropharyngeal Swabs Do Not Rule Out COVID-19. J Clin Microbiol. 2020; 58(5).
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