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Published online: 2021-04-12
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Factors affecting the choice of drospirenone as the component of combined contraceptive pill in daily clinical practice: the results of nation-wide survey

Magdalena Olszanecka-Glinianowicz, Violetta Skrzypulec-Plinta
DOI: 10.5603/GP.a2021.0015
·
Pubmed: 33844254

open access

Ahead of Print
ORIGINAL PAPERS Gynecology
Published online: 2021-04-12

Abstract

Objectives: The aim of the multicenter, open-label, post-marketing, observational survey was to assess doctors’ preferences
in choosing the progestogen component of the combined contraceptive pill (CCP) and factors affecting this choice in daily
clinical practice as well as non-contraceptive reasons use of CCP containing drospirenone (CCPD) and patients’ tolerance
and satisfaction with the treatment.
Material and methods: This multicenter, open-label, post-marketing, survey was performed nation-wide with the participation
of 222 doctors involving and 10,345 patients treated with CCPD.
The study questionnaire included questions concerning factors affecting the choice of drospirenone as a component of
CCP and assessing prescription pattern of the drug as well as tolerance and satisfaction with the use of CCPD.
Results: The doctors frequently declared their choice of drospirenone as the progestogen component of CCP. The most
important factors affecting the choice of drospirenone, declared by doctors, were tolerance level, consistent regulation of
menstrual cycle and not causing spotting.
CCPD was prescribed to patients with irregular menstrual cycles (62.7%) and painful menstruation (46.8%).
During follow-up, significantly increased percentage of patients assessed the tolerance of treatment with CCPD as very
good (52.5% vs 68.0%; p < 0.01) and very satisfied with its use (61.9% vs 77.8%, p < 0.01).
Conclusions: 1) Drospirenone is frequently chosen progestogen component in CCP by Polish gynecologists due to its good
tolerance, consistent regulation of the menstrual cycle and no spotting in patients opinion. 2) CCPD was most frequently
used in patients with irregular menstrual cycles and painful menstruation. 3) The patients were satisfied with the use CCPD
and treatment was well tolerated.

Abstract

Objectives: The aim of the multicenter, open-label, post-marketing, observational survey was to assess doctors’ preferences
in choosing the progestogen component of the combined contraceptive pill (CCP) and factors affecting this choice in daily
clinical practice as well as non-contraceptive reasons use of CCP containing drospirenone (CCPD) and patients’ tolerance
and satisfaction with the treatment.
Material and methods: This multicenter, open-label, post-marketing, survey was performed nation-wide with the participation
of 222 doctors involving and 10,345 patients treated with CCPD.
The study questionnaire included questions concerning factors affecting the choice of drospirenone as a component of
CCP and assessing prescription pattern of the drug as well as tolerance and satisfaction with the use of CCPD.
Results: The doctors frequently declared their choice of drospirenone as the progestogen component of CCP. The most
important factors affecting the choice of drospirenone, declared by doctors, were tolerance level, consistent regulation of
menstrual cycle and not causing spotting.
CCPD was prescribed to patients with irregular menstrual cycles (62.7%) and painful menstruation (46.8%).
During follow-up, significantly increased percentage of patients assessed the tolerance of treatment with CCPD as very
good (52.5% vs 68.0%; p < 0.01) and very satisfied with its use (61.9% vs 77.8%, p < 0.01).
Conclusions: 1) Drospirenone is frequently chosen progestogen component in CCP by Polish gynecologists due to its good
tolerance, consistent regulation of the menstrual cycle and no spotting in patients opinion. 2) CCPD was most frequently
used in patients with irregular menstrual cycles and painful menstruation. 3) The patients were satisfied with the use CCPD
and treatment was well tolerated.

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Keywords

combined contraceptive pill containing drospirenone; doctors’ preferences; patients’ satisfaction; tolerance

About this article
Title

Factors affecting the choice of drospirenone as the component of combined contraceptive pill in daily clinical practice: the results of nation-wide survey

Journal

Ginekologia Polska

Issue

Ahead of Print

Article type

Research paper

Published online

2021-04-12

DOI

10.5603/GP.a2021.0015

Pubmed

33844254

Keywords

combined contraceptive pill containing drospirenone
doctors’ preferences
patients’ satisfaction
tolerance

Authors

Magdalena Olszanecka-Glinianowicz
Violetta Skrzypulec-Plinta

References (20)
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