open access

Vol 92, No 1 (2021)
Clinical vignette
Published online: 2020-12-15
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Long-term response to hormone therapy in a young woman with aggressive pelvic angiomyxoma

Klaudia Walczak1, Kamila Luczynska1, Jolanta Kupryjanczyk2, Renata Duchnowska3
DOI: 10.5603/GP.a2020.0183
Pubmed: 33448013
Ginekol Pol 2021;92(1):82-83.
  1. Student Scientific Circle „Spero“, Department of Oncology, Military Institute of Medicine, Warsaw, Poland
  2. Department of Pathology National Cancer Institute, Warsaw, Poland
  3. Department of Oncology, Military Institute of Medicine, Warsaw, Poland, Warsaw, Poland

open access

Vol 92, No 1 (2021)
Published online: 2020-12-15


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Not available
Get Citation


aggressive angiomyxoma, antiestrogen therapy, pelvic tumor

About this article

Long-term response to hormone therapy in a young woman with aggressive pelvic angiomyxoma


Ginekologia Polska


Vol 92, No 1 (2021)

Article type

Clinical vignette



Published online






Bibliographic record

Ginekol Pol 2021;92(1):82-83.


aggressive angiomyxoma
antiestrogen therapy
pelvic tumor


Klaudia Walczak
Kamila Luczynska
Jolanta Kupryjanczyk
Renata Duchnowska

References (17)
  1. Chen H, Zhao H, Xie Y, et al. Clinicopathological features and differential diagnosis of aggressive angiomyxoma of the female pelvis: 5 case reports and literature review. Medicine (Baltimore). 2017; 96(20): e6820.
  2. Sun Y, Zhu L, Chang X, et al. Clinicopathological Features and Treatment Analysis of Rare Aggressive Angiomyxoma of the Female Pelvis and Perineum - a Retrospective Study. Pathol Oncol Res. 2017; 23(1): 131–137.
  3. Haldar K, Martinek IE, Kehoe S. Aggressive angiomyxoma: a case series and literature review. Eur J Surg Oncol. 2010; 36(4): 335–339.
  4. Schwartz PE, Hui P, McCarthy S. Hormonal therapy for aggressive angiomyxoma: a case report and proposed management algorithm. J Low Genit Tract Dis. 2014; 18(2): E55–E61.
  5. Hajjar R, Alharthi M, Richard C, et al. Pelvic Aggressive Angiomyxoma: Major Challenges in Diagnosis and Treatment. Cureus. 2019; 11(4): e4419.
  6. Aguilar-Frasco J, Ruben-Castillo C, Rodríguez-Quintero JH, et al. Aggressive angiomyxoma: giant recurrence successfully treated with wide excision and adjuvant therapy with GnRH analogue. BMJ Case Rep. 2018; 11(1).
  7. Alobaid A, Goffin F, Lussier C, et al. Aggressive Angiomyxoma of the Vulva or Perineum: Report of Three Patients. J Obstet Gynaecol Can. 2005; 27(11): 1023–1026.
  8. Aye C, Jefferis H, Chung DY, et al. A case of multi-modal managed vulval aggressive angiomyxoma diagnosed before conception and monitored during pregnancy. Gynecol Oncol. 2009; 115(1): 170–171.
  9. Bai HM, Yang JX, Huang HF, et al. Individualized managing strategies of aggressive angiomyxoma of female genital tract and pelvis. Eur J Surg Oncol. 2013; 39(10): 1101–1108.
  10. Fine BA, Munoz AK, Litz CE, et al. Primary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist. Gynecol Oncol. 2001; 81(1): 120–122.
  11. Fucà G, Hindi N, Ray-Coquard I, et al. Treatment Outcomes and Sensitivity to Hormone Therapy of Aggressive Angiomyxoma: A Multicenter, International, Retrospective Study. Oncologist. 2019; 24(7): e536–e541.
  12. Im SW, Han SSu. Treatment of aggressive angiomyxoma of the female perineum: Combined operative and hormone therapy. J Obstet Gynaecol. 2016; 36(6): 819–821.
  13. McCluggage WG, Jamieson T, Dobbs SP, et al. Aggressive angiomyxoma of the vulva: Dramatic response to gonadotropin-releasing hormone agonist therapy. Gynecol Oncol. 2006; 100(3): 623–625.
  14. Palomba S, Oppedisano R, Annunziata G, et al. Leuprolide acetate depot plus high-dose raloxifene hydrochloride before and after surgery for recurrent vaginal aggressive angiomyxoma: a case report. Gynecol Oncol. 2011; 123(1): 172–173.
  15. Abu JI, Bamford WM, Malin G, et al. Aggressive angiomyxoma of the perineum. Int J Gynecol Cancer. 2005; 15(6): 1097–1100.
  16. Magtibay PM, Salmon Z, Keeney GL, et al. Aggressive angiomyxoma of the female pelvis and perineum: a case series. Int J Gynecol Cancer. 2006; 16(1): 396–401.
  17. Giles DL, Liu PT, Lidner TK, et al. Treatment of aggressive angiomyxoma with aromatase inhibitor prior to surgical resection. Int J Gynecol Cancer. 2008; 18(2): 375–379.


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