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Published online: 2020-12-09
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Evaluation of inflammatuar response in hysterectomies: a retrospective study in Kocaeli, Turkey

Mehmet Özsürmeli, Ünal Türkay, Bahar Salıcı, Mehmet Salıcı, Karanfil Nisan Bölge, Hasan Terzi
DOI: 10.5603/GP.a2020.0146
·
Pubmed: 33448002

open access

Ahead of Print
ORIGINAL PAPERS Gynecology
Published online: 2020-12-09

Abstract

Objectives: The authors aimed to detect the inflammatory marker changes in laparoscopic hysterectomy (LH) and abdominal
hysterectomy (AH) and to determine whether oophorectomy affected the results.
Material and methods: The patients who underwent LH and AH with or without oophorectomy between 2018 and
2019 were identified as two groups. The records of patients were reviewed retrospectively. Preoperative and postoperative
in the first 24 hours hematocrit (HCT), hemoglobin (HB), white blood cell (WBC), platelet-lymphocyte ratio (PLR), and
neutrophil-lymphocyte ratio (NLR) values were compared.
Results: WBC, NLR, and PLR were statistically increased, and HB and HCT were decreased in all groups in the postoperative
period. However, all changes were more prominent in the AH group than in the LH group. In other words, in the postoperative
period, there were fewer changes in the inflammatory markers WBC, NLR, and NLR in the LH group. Oophorectomy
did not affect these results.
Conclusions: LH, as in other laparoscopic operations, was associated with lower inflammatory response. The addition
of oophorectomy did not increase inflammation in either AH or LH. Clinical Trials registration number is NCT04184765.

Abstract

Objectives: The authors aimed to detect the inflammatory marker changes in laparoscopic hysterectomy (LH) and abdominal
hysterectomy (AH) and to determine whether oophorectomy affected the results.
Material and methods: The patients who underwent LH and AH with or without oophorectomy between 2018 and
2019 were identified as two groups. The records of patients were reviewed retrospectively. Preoperative and postoperative
in the first 24 hours hematocrit (HCT), hemoglobin (HB), white blood cell (WBC), platelet-lymphocyte ratio (PLR), and
neutrophil-lymphocyte ratio (NLR) values were compared.
Results: WBC, NLR, and PLR were statistically increased, and HB and HCT were decreased in all groups in the postoperative
period. However, all changes were more prominent in the AH group than in the LH group. In other words, in the postoperative
period, there were fewer changes in the inflammatory markers WBC, NLR, and NLR in the LH group. Oophorectomy
did not affect these results.
Conclusions: LH, as in other laparoscopic operations, was associated with lower inflammatory response. The addition
of oophorectomy did not increase inflammation in either AH or LH. Clinical Trials registration number is NCT04184765.

Get Citation

Keywords

hysterectomies; inflammation mediators; lymphocyte activation; neutrophil activation; platelet activation

About this article
Title

Evaluation of inflammatuar response in hysterectomies: a retrospective study in Kocaeli, Turkey

Journal

Ginekologia Polska

Issue

Ahead of Print

Article type

Research paper

Published online

2020-12-09

DOI

10.5603/GP.a2020.0146

Pubmed

33448002

Keywords

hysterectomies
inflammation mediators
lymphocyte activation
neutrophil activation
platelet activation

Authors

Mehmet Özsürmeli
Ünal Türkay
Bahar Salıcı
Mehmet Salıcı
Karanfil Nisan Bölge
Hasan Terzi

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