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Placental mesenchymal dysplasia and hepatic cyst
Affiliations- 2nd Department of Gynecology and Obstetrics, Wroclaw Medical University, Wroclaw, Poland
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Abstract
Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as
a molar pregnancy resulting in unnecessary termination of pregnancy.
A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound
showed a bulky placenta with multiple cysts. Oligohydramnion and fetal hypoechogenic cystic area without doppler flow
were diagnosed at 23 weeks. The baby was operated on after delivery, and an 80 mm multifocal cyst originating from the right
lobe of the liver was removed. The placenta demonstrated swelling stem villi with enlarged vessels and increased interstitial
cells without trophoblast proliferation. PMD and fetal hepatic cyst can coexist; however, the relationship between those
conditions remains to be elucidated. PMD is associated with adverse pregnancy outcomes but also with a good prognosis.
Abstract
Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as
a molar pregnancy resulting in unnecessary termination of pregnancy.
A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound
showed a bulky placenta with multiple cysts. Oligohydramnion and fetal hypoechogenic cystic area without doppler flow
were diagnosed at 23 weeks. The baby was operated on after delivery, and an 80 mm multifocal cyst originating from the right
lobe of the liver was removed. The placenta demonstrated swelling stem villi with enlarged vessels and increased interstitial
cells without trophoblast proliferation. PMD and fetal hepatic cyst can coexist; however, the relationship between those
conditions remains to be elucidated. PMD is associated with adverse pregnancy outcomes but also with a good prognosis.
Keywords
placental mesenchymal dysplasia; hepatic cyst
About this articleTitle
Placental mesenchymal dysplasia and hepatic cyst
Journal
Issue
Article type
Clinical vignette
Pages
779-780
Published online
2020-11-24
Page views
994
Article views/downloads
940
DOI
Pubmed
Bibliographic record
Ginekol Pol 2020;91(12):779-780.
Keywords
placental mesenchymal dysplasia
hepatic cyst
Authors
Anna Rosner-Tenerowicz
Michal Pomorski
Tomasz Fuchs
Jakub Sliwa
Aleksandra Zimmer-Stelmach
Wiktor Bek
Mariusz Zimmer
References (4)- Arizawa M, Nakayama M. Suspected involvement of the X chromosome in placental mesenchymal dysplasia. Congenit Anom (Kyoto). 2002; 42(4): 309–317.
- Thompson JMD, Irgens LM, Skjaerven R, et al. Placenta weight percentile curves for singleton deliveries. BJOG. 2007; 114(6): 715–720.
- Nayeri UA, West AB, Grossetta Nardini HK, et al. Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 2013; 41(4): 366–374.
- H'mida D, Gribaa M, Yacoubi T, et al. Placental mesenchymal dysplasia with beckwith-wiedemann syndrome fetus in the context of biparental and androgenic cell lines. Placenta. 2008; 29(5): 454–460.
