open access

Vol 89, No 11 (2018)
ORIGINAL PAPERS Gynecology
Published online: 2018-11-30
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Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy

Sieun Han, Hyunjoo Lee, Seungchul Kim, Jongkil Joo, Dongsoo Suh, Kihyung Kim, Kyusup Lee
DOI: 10.5603/GP.a2018.0105
·
Pubmed: 30508213
·
Ginekol Pol 2018;89(11):611-617.

open access

Vol 89, No 11 (2018)
ORIGINAL PAPERS Gynecology
Published online: 2018-11-30

Abstract

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence of ovarian endometrioma after ovarian cystectomy in Korean women with long-term postoperative medical therapy.
Material and Methods: A total of 134 patients who were surgically treated for endometriotic cysts at Pusan National University Hospital were included in this retrospective study. All patients received long-term postoperative medical treatment for at least 12 months after the first-line conservative surgery. Several epidemiologic variables were analyzed as possible risk factors for recurrence. Endometrioma recurrence was considered when a cystic mass was observed on transvaginal or transrectal sonography. Statistical analysis was performed using independent t-tests for parametric continuous variables.
Results: The mean follow-up period for the 134 patients was 56.5 ± 14.3 months (range, 36–120 months) and the mean duration of the medical therapy was 17.9 ± 17.3 months (range, 12–120 months). The overall recurrence rate was 35/134 (26.12%). Our univariate analysis showed statistically significant differences between the recurrent and non-recurrent groups in terms of weight (P = 0.013), body mass index (P = 0.007), age at the time of surgery (P = 0.013), the diameter of the largest cyst (P = 0.001), the presence of dysmenorrhea (P < 0.0001), and postoperative pregnancy (P = 0.016). Multivariate analysis showed that body mass index (OR 1.153, 95% CI 1.003–1.326, P = 0.046), age at the time of surgery (OR 0.924, 95% CI 0.860–0.992, P = 0.029), and presence of dysmenorrhea (OR 12.226, 95% CI 3.543–42.188, P < 0.0001) were significantly correlated with the recurrence of endometrioma.
Conclusions: We found that patients with dysmenorrhea after surgery, and a younger age of the patient at the time of surgery were the highest risk factors associated with the recurrence of endometrioma, despite long-term postoperative medication.

Abstract

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence of ovarian endometrioma after ovarian cystectomy in Korean women with long-term postoperative medical therapy.
Material and Methods: A total of 134 patients who were surgically treated for endometriotic cysts at Pusan National University Hospital were included in this retrospective study. All patients received long-term postoperative medical treatment for at least 12 months after the first-line conservative surgery. Several epidemiologic variables were analyzed as possible risk factors for recurrence. Endometrioma recurrence was considered when a cystic mass was observed on transvaginal or transrectal sonography. Statistical analysis was performed using independent t-tests for parametric continuous variables.
Results: The mean follow-up period for the 134 patients was 56.5 ± 14.3 months (range, 36–120 months) and the mean duration of the medical therapy was 17.9 ± 17.3 months (range, 12–120 months). The overall recurrence rate was 35/134 (26.12%). Our univariate analysis showed statistically significant differences between the recurrent and non-recurrent groups in terms of weight (P = 0.013), body mass index (P = 0.007), age at the time of surgery (P = 0.013), the diameter of the largest cyst (P = 0.001), the presence of dysmenorrhea (P < 0.0001), and postoperative pregnancy (P = 0.016). Multivariate analysis showed that body mass index (OR 1.153, 95% CI 1.003–1.326, P = 0.046), age at the time of surgery (OR 0.924, 95% CI 0.860–0.992, P = 0.029), and presence of dysmenorrhea (OR 12.226, 95% CI 3.543–42.188, P < 0.0001) were significantly correlated with the recurrence of endometrioma.
Conclusions: We found that patients with dysmenorrhea after surgery, and a younger age of the patient at the time of surgery were the highest risk factors associated with the recurrence of endometrioma, despite long-term postoperative medication.

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Keywords

endometrioma; recurrence rate; cystectomy; endometriosis

About this article
Title

Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy

Journal

Ginekologia Polska

Issue

Vol 89, No 11 (2018)

Pages

611-617

Published online

2018-11-30

DOI

10.5603/GP.a2018.0105

Pubmed

30508213

Bibliographic record

Ginekol Pol 2018;89(11):611-617.

Keywords

endometrioma
recurrence rate
cystectomy
endometriosis

Authors

Sieun Han
Hyunjoo Lee
Seungchul Kim
Jongkil Joo
Dongsoo Suh
Kihyung Kim
Kyusup Lee

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