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Diagnostic hysteroscopy and the risk of malignant cells intraabdominal spread in women with endometrial cancer
Affiliations- Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, Poland, ul. Chodźki 1, 20-093 Lublin, Poland
- I Chair and Department of Oncological Gynaecology and Gynecology, Medical University of Lublin, Poland, ul. Staszica 16, 20-081 Lublin, Poland
- Department of Obstetrics and Gynaecology Pro-Familia Hospital, Rzeszow, Poland
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Abstract
Although hysteroscopy is currently the undisputed gold standard for the examination of the uterine cavity in women with suspected endometrial cancer, it remains controversial as a procedure that can enhance metastasis spread. Endometrial cancer cells may shed during hysteroscopy and be passively transported with fluid flow into the peritoneal cavity. The paper presents the review of current knowledge regarding the risk of neoplasm metastases in women who had diagnostic hysteroscopy and the conditions that have to be met for the procedure to be safe. We searched PubMed, Ovid, Medline and Scopus databases for data published in the years 1985–2017. The following browsing criteria, the “MeSH headings”: hysteroscopy, endometrial cancer, intraperitoneal or metastatic spread were used to find relevant papers. Based on the current data analysis we conclude that (1.) diagnostic hysteroscopy performed in women with endometrial cancer, especially in its early stages, is a very useful, efficient and safe diagnostic method and (2.) the distension media used for endoscopic procedures in the uterine cavity must be strictly controlled for relatively low pressures to prevent the increase in risk of endometrial cancer intraperitoneal spread.
Abstract
Although hysteroscopy is currently the undisputed gold standard for the examination of the uterine cavity in women with suspected endometrial cancer, it remains controversial as a procedure that can enhance metastasis spread. Endometrial cancer cells may shed during hysteroscopy and be passively transported with fluid flow into the peritoneal cavity. The paper presents the review of current knowledge regarding the risk of neoplasm metastases in women who had diagnostic hysteroscopy and the conditions that have to be met for the procedure to be safe. We searched PubMed, Ovid, Medline and Scopus databases for data published in the years 1985–2017. The following browsing criteria, the “MeSH headings”: hysteroscopy, endometrial cancer, intraperitoneal or metastatic spread were used to find relevant papers. Based on the current data analysis we conclude that (1.) diagnostic hysteroscopy performed in women with endometrial cancer, especially in its early stages, is a very useful, efficient and safe diagnostic method and (2.) the distension media used for endoscopic procedures in the uterine cavity must be strictly controlled for relatively low pressures to prevent the increase in risk of endometrial cancer intraperitoneal spread.
Keywords
hysteroscopy, endometrial cancer, intraabdominal cancer cells spread
About this articleTitle
Diagnostic hysteroscopy and the risk of malignant cells intraabdominal spread in women with endometrial cancer
Journal
Issue
Article type
Review paper
Pages
562-567
Published online
2017-10-31
Page views
2530
Article views/downloads
2980
DOI
Pubmed
Bibliographic record
Ginekol Pol 2017;88(10):562-567.
Keywords
hysteroscopy
endometrial cancer
intraabdominal cancer cells spread
Authors
Norbert Stachowicz
Diana Mazurek
Tomasz Łoziński
Artur Czekierdowski
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