Vol 88, No 2 (2017)
Research paper
Published online: 2017-02-28

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Labour in women with gestational diabetes mellitus

Klaudia Grabowska, Angelika Stapińska-Syniec, Aleksandra Saletra, Patrycja Jarmużek, Dorota Bomba-Opoń
Pubmed: 28326517
Ginekol Pol 2017;88(2):81-86.

Abstract

Objectives: Gestational diabetes mellitus (GDM) constitutes one of the most common pregnancy complications and affects 3–5% of all pregnancies, with its incidence still growing. Due to possible maternal and fetal complications, the peripartum management of GDM patients continues to be a debatable issue. The aim of the study was to analyse the course and final way of delivery in women with gestational diabetes mellitus. The effectiveness of induction of labour (IOL) was also assessed and factors predisposing to cesarean section were identified.

Material and methods: The study group consisted of 204 women with GDM who delivered in the Academic Centre for Woman’s and Neonate’s Health in Warsaw over the years 2013 and 2014. The indications and ratios of elective and intrapartum cesarean sections were analysed. Patients qualified for induction of labour were compared depending on their final way of delivery.

Results: Over a half of all deliveries in the study group (53%) were cesarean sections. Elective surgeries accounted for 70% of all cesarean sections, predominantly due to a history of previous operational deliveries. Only 12% of the study group developed spontaneous uterine contractions and delivered vaginally. A comparison of the vaginal delivery group (n = 96) with cesarean section group (n = 108) pointed to high pregestational BMI value and advanced maternal age as factors increasing the patient’s risk for surgical delivery (p = 0.0000 and p = 0.048 accordingly). The comparison of women undergo­ing IOL vs. omen with spontaneous uterine contractions showed no increase in the ratio of intrapartum cesarean sections in the IOL group — in both subgroups vaginal delivery was achieved in 75% of cases.

Conclusions: Patients with GDM are more likely to undergo cesarean section, but the implementation of induction of labour at term does not further aggravate this risk. Major risk factors for operational delivery in GDM population included: advanced maternal age, high pregestational BMI value and undergoing insulin therapy.

References

  1. Bas-Lando M, Srebnik N, Farkash R, et al. Elective induction of labor in women with gestational diabetes mellitus: an intervention that modifies the risk of cesarean section. Arch Gynecol Obstet. 2014; 290(5): 905–912.
  2. DeSisto CL, Kim SY, Sharma AJ. Prevalence estimates of gestational diabetes mellitus in the United States, Pregnancy Risk Assessment Monitoring System (PRAMS), 2007-2010. Prev Chronic Dis. 2014; 11: E104.
  3. Schneider S, Bock C, Wetzel M, et al. The prevalence of gestational diabetes in advanced economies. J Perinat Med. 2012; 40(5): 511–520.
  4. Wójcikowski C, Królikowska B, Konarzewska J, et al. The prevalence of gestational diabetes mellitus in Polish population. Ginekol Pol. 2002; 73(10): 811–816.
  5. Kleinwechter H, Schäfer-Graf U, Bührer C, et al. Gestational Diabetes Mellitus (GDM) Diagnosis, Therapy and Follow-Up Care. Experimental and Clinical Endocrinology & Diabetes. 2014; 122(07): 395–405.
  6. Lawrence JM, Contreras R, Chen W, et al. Trends in the prevalence of preexisting diabetes and gestational diabetes mellitus among a racially/ethnically diverse population of pregnant women, 1999-2005. Diabetes Care. 2008; 31(5): 899–904.
  7. Kinalski M, Śledziewski A, Kuźmicki M, et al. Wskaźniki ryzyka ujawnienia się cukrzycy ciężarnych. Diabetologia Praktyczna. 2003; 4(4): 257–263.
  8. Flack JR, Ross GP, Ho S, et al. Recommended changes to diagnostic criteria for gestational diabetes: impact on workload. Aust N Z J Obstet Gynaecol. 2010; 50(5): 439–443.
  9. Gorgal R, Gonçalves E, Barros M, et al. Gestational diabetes mellitus: a risk factor for non-elective cesarean section. J Obstet Gynaecol Res. 2012; 38(1): 154–159.
  10. Srichumchit S, Luewan S, Tongsong T. Outcomes of pregnancy with gestational diabetes mellitus. Int J Gynaecol Obstet. 2015; 131(3): 251–254.
  11. Boulvain M, Senat MV, Perrotin F, et al. Groupe de Recherche en Obstétrique et Gynécologie (GROG). Induction of labour versus expectant management for large-for-date fetuses: a randomised controlled trial. Lancet. 2015; 385(9987): 2600–2605.
  12. Wender-Ozegowska E, Bomba-Opoń D, Brazert J, et al. Polish Gynecological Society. [Polish Gynecological Society standards of medical care in management of women with diabetes]. Ginekol Pol. 2011; 82(6): 474–479.
  13. Ovesen PG, Jensen DM, Damm P, et al. Maternal and neonatal outcomes in pregnancies complicated by gestational diabetes. a nation-wide study. J Matern Fetal Neonatal Med. 2015; 28(14): 1720–1724.
  14. Wei YM, Yang HX, Zhu WW, et al. Effects of intervention to mild GDM on outcomes. J Matern Fetal Neonatal Med. 2015; 28(8): 928–931.
  15. Wender-Ozegowska E, Bomba-Opoń D, Brazert J, et al. Actualisation of Polish Gyneacological Society standards of medical care in management of women with diabetes. Ginekol Pol. 2014; 85(6): 476–478.
  16. Caughey AB, Sundaram V, Kaimal AJ, et al. Systematic review: elective induction of labor versus expectant management of pregnancy. Ann Intern Med. 2009; 151(4): 252–63, W53.
  17. Wood S, Cooper S, Ross S. Does induction of labour increase the risk of caesarean section? A systematic review and meta-analysis of trials in women with intact membranes. BJOG. 2014; 121(6): 674–685.
  18. Kjos SL, Henry OA, Montoro M, et al. Insulin-requiring diabetes in pregnancy: a randomized trial of active induction of labor and expectant management. Am J Obstet Gynecol. 1993; 169(3): 611–615.
  19. Witkop CT, Neale D, Wilson LM, et al. Active compared with expectant delivery management in women with gestational diabetes: a systematic review. Obstet Gynecol. 2009; 113(1): 206–217.
  20. Niu B, Lee VR, Cheng YW, et al. What is the optimal gestational age for women with gestational diabetes type A1 to deliver? Am J Obstet Gynecol. 2014; 211(4): 418.e1–e6.
  21. Gülmezoglu AM, Crowther CA, Middleton P, et al. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database Syst Rev. 2012; 6: CD004945.
  22. Vilchez GA, Dai J, Hoyos LR, et al. Labor and neonatal outcomes after term induction of labor in gestational diabetes. J Perinatol. 2015; 35(11): 924–929.
  23. Maso G, Alberico S, Wiesenfeld U, et al. "GINEXMAL RCT: Induction of labour versus expectant management in gestational diabetes pregnancies". BMC Pregnancy and Childbirth. 2011; 11(1).