open access

Vol 91, No 7 (2020)
REVIEW PAPERS Obstetrics
Published online: 2020-07-31
Get Citation

COVID-19 during pregnancy, delivery and postpartum period based on EBM

Patrycja Stanczyk, Tomasz Jachymski, Piotr Sieroszewski
DOI: 10.5603/GP.2020.0106
·
Pubmed: 32779163
·
Ginekol Pol 2020;91(7):417-423.

open access

Vol 91, No 7 (2020)
REVIEW PAPERS Obstetrics
Published online: 2020-07-31

Abstract

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the reason of the
global health crisis. Since the first case of diagnosed COVID-19 pneumonia was reported in Wuhan, Hubei Province, China,
in December 2019, the infection has spread rapidly to all over the world.
The knowledge gained from previous human coronavirus infection outbreaks suggests that pregnant women and their
foetuses represent a high-risk population during infectious disease epidemics.
Moreover, a pregnancy, due to the physiological changes involving immune and cardiopulmonary systems, is a state
predisposing women to respiratory complications of viral infection.
The constantly increasing number of publications regarding the course of COVID-19 infection in pregnant women has been
published, however, the available data remains limited and many questions remain unanswered. The aim of this review
was to summarize the literature data and adjusted to current recommendations regarding pregnancy care, delivery and
postpartum period.
An extremely important issue is the need to register all the cases of COVID-19 affected women and the course of these
pregnancies to local, regional, or international registries, which will be helpful to answer many clinical and scientific questions
and to create guidelines ensuring an adequate level of care for women affected by COVID-19 infection during pregnancy,
delivery and during postpartum period, as well as their newborns.

Abstract

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the reason of the
global health crisis. Since the first case of diagnosed COVID-19 pneumonia was reported in Wuhan, Hubei Province, China,
in December 2019, the infection has spread rapidly to all over the world.
The knowledge gained from previous human coronavirus infection outbreaks suggests that pregnant women and their
foetuses represent a high-risk population during infectious disease epidemics.
Moreover, a pregnancy, due to the physiological changes involving immune and cardiopulmonary systems, is a state
predisposing women to respiratory complications of viral infection.
The constantly increasing number of publications regarding the course of COVID-19 infection in pregnant women has been
published, however, the available data remains limited and many questions remain unanswered. The aim of this review
was to summarize the literature data and adjusted to current recommendations regarding pregnancy care, delivery and
postpartum period.
An extremely important issue is the need to register all the cases of COVID-19 affected women and the course of these
pregnancies to local, regional, or international registries, which will be helpful to answer many clinical and scientific questions
and to create guidelines ensuring an adequate level of care for women affected by COVID-19 infection during pregnancy,
delivery and during postpartum period, as well as their newborns.

Get Citation

Keywords

COVID-19; SARS-CoV-2; coronavirus; pandemic; pregnancy; respiratory distress syndrome

About this article
Title

COVID-19 during pregnancy, delivery and postpartum period based on EBM

Journal

Ginekologia Polska

Issue

Vol 91, No 7 (2020)

Pages

417-423

Published online

2020-07-31

DOI

10.5603/GP.2020.0106

Pubmed

32779163

Bibliographic record

Ginekol Pol 2020;91(7):417-423.

Keywords

COVID-19
SARS-CoV-2
coronavirus
pandemic
pregnancy
respiratory distress syndrome

Authors

Patrycja Stanczyk
Tomasz Jachymski
Piotr Sieroszewski

References (57)
  1. Pyrć K. Ludzkie koronawirusy. Postępy Nauk Medycznych. 2015; XXVIII(4B).
  2. van der Hoek L, Pyrc K, Berkhout B. Human coronavirus NL63, a new respiratory virus. FEMS Microbiol Rev. 2006; 30(5): 760–773.
  3. Zaki AM, van Boheemen S, Bestebroer TM, et al. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012; 367(19): 1814–1820.
  4. Abramczuk E, et al. Niepandemiczne koronawirusy człowieka – charakterystyka i diagnostyka. POST. MIKROBIOL. 2017; 56(2): 205–213.
  5. Vijaykrishna D, Smith GJD, Zhang JX, et al. Evolutionary insights into the ecology of coronaviruses. J Virol. 2007; 81(8): 4012–4020.
  6. Vabret A, Dina J, Brison E, et al. [Human coronaviruses]. Pathol Biol (Paris). 2009; 57(2): 149–160.
  7. Hamre D, Procknow JJ. A new virus isolated from the human respiratory tract. Proc Soc Exp Biol Med. 1966; 121(1): 190–193.
  8. Ksiazek TG, Erdman D, Goldsmith CS, et al. SARS Working Group. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003; 348(20): 1953–1966.
  9. Rota PA, Oberste MS, Monroe SS, et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science. 2003; 300(5624): 1394–1399.
  10. Cheng VCC, Chan JFW, To KKW, et al. Clinical management and infection control of SARS: lessons learned. Antiviral Res. 2013; 100(2): 407–419.
  11. Plipat T, Buathong R, Wacharapluesadee S, et al. Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015. Euro Surveill. 2017; 22(33).
  12. Bogoch II, Watts A, Thomas-Bachli A, et al. Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travel. J Travel Med. 2020; 27(2).
  13. https://www.ecdc.europa.eu/en/geographical-distribution-2019-ncov-cases.
  14. Sun Z, Thilakavathy K, Kumar SS, et al. Potential Factors Influencing Repeated SARS Outbreaks in China. Int J Environ Res Public Health. 2020; 17(5).
  15. Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020; 109: 102433.
  16. Xiao F, Hiremath S, Knoll G, et al. Increased urinary angiotensin-converting enzyme 2 in renal transplant patients with diabetes. PLoS One. 2012; 7(5): e37649.
  17. Sun P, Lu X, Xu C, et al. Understanding of COVID-19 based on current evidence. J Med Virol. 2020; 92(6): 548–551.
  18. Karlberg J, Chong DSY, Lai WYY. Do men have a higher case fatality rate of severe acute respiratory syndrome than women do? Am J Epidemiol. 2004; 159(3): 229–231.
  19. Peng L, Liu J, Xu W, et al. SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens. J Med Virol. 2020 [Epub ahead of print].
  20. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19), 16-24 February 2020.
  21. Prisant N, Bujan L, Benichou H, et al. Zika virus in the female genital tract. Lancet Infect Dis. 2016; 16(9): 1000–1001.
  22. Rodriguez LL, De Roo A, Guimard Y, et al. Persistence and genetic stability of Ebola virus during the outbreak in Kikwit, Democratic Republic of the Congo, 1995. J Infect Dis. 1999; 179 Suppl 1: S170–S176.
  23. Qiu L, Liu X, Xiao M, et al. SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection. Clin Infect Dis. 2020 [Epub ahead of print].
  24. Cui P, Chen Z, Wang T, et al. Clinical features and sexual transmission potential of SARS-CoV-2 infected female patients: a descriptive study in Wuhan, China. .
  25. O'Day MP. Cardio-respiratory physiological adaptation of pregnancy. Semin Perinatol. 1997; 21(4): 268–275.
  26. Dashraath P, Wong JL, Lim MX, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 2020; 222(6): 521–531.
  27. Nelson-Piercy C. Respiratory disease. In: Nelson-Piercy C. ed. Handbook of Obstetric Medicine. CRC Press, Boca Raton, FL 2015: 63–84.
  28. Schwartz DA, Graham AL. Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses. 2020; 12(2).
  29. https://cgf.cochrane.org/news/covid- 19-koronawirus-choroba-płodność-i-ciąża.
  30. https://nl.surveymonkey.com/r/COVID19ART.
  31. https://www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/covid-19/covidtaskforce.pdf.
  32. Assisted reproduction and COVID-19. A statement from ESHRE for phase 1 - Guidance on fertility services during pandemic. https://www.eshre.eu/Press-Room/ESHRE-News#CoronaStatement27feb.
  33. https://www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/covid-19/asrm-eshre-iffs-joint-statement.pdf.
  34. http://www.ptgin.pl/koronawirus-covid-19-stanowisko-w-kwestii-leczenia-nieplodnosci.
  35. Zhang Jp, Wang Yh, Chen Ln, et al. [Clinical analysis of pregnancy in second and third trimesters complicated severe acute respiratory syndrome]. Zhonghua Fu Chan Ke Za Zhi. 2003; 38(8): 516–520.
  36. Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020; 99(7): 823–829.
  37. Breslin N, Baptiste C, Gyamfi-Bannerman C, et al. COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstet Gynecol MFM. 2020 [Epub ahead of print]: 100118.
  38. Breslin N, Baptiste C, Miller R, et al. Coronavirus disease 2019 in pregnancy: early lessons. Am J Obstet Gynecol MFM. 2020; 2(2): 100111.
  39. Mullins E, Evans D, Viner RM, et al. Coronavirus in pregnancy and delivery: rapid review. Ultrasound Obstet Gynecol. 2020; 55(5): 586–592.
  40. Ng WF, Wong SF, Lam A, et al. The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation. Pathology. 2006; 38(3): 210–218.
  41. Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020; 9(1): 51–60.
  42. Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020; 395(10226): 809–815.
  43. Lei D, Wang C, Li C, et al. Clinical characteristics of COVID-19 in pregnancy: analysis of nine cases. Chin J Perinat Med. 2020; 23(03): 225–231.
  44. Zeng H, Xu C, Fan J, et al. Antibodies in Infants Born to Mothers With COVID-19 Pneumonia. JAMA. 2020 [Epub ahead of print].
  45. Dong L, Tian J, He S, et al. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. 2020 [Epub ahead of print].
  46. Kimberlin DW, Stagno S. Can SARS-CoV-2 Infection Be Acquired In Utero?: More Definitive Evidence Is Needed. JAMA. 2020 [Epub ahead of print].
  47. Wang S, Guo L, Chen L, et al. A case report of neonatal COVID-19 infection in China. Clin Infect Dis. 2020 [Epub ahead of print].
  48. Zalecenie Sekcji Ultrasonografii PTGIP w zakresie badań USG w sytuacji epidemiologicznej - COVID-19. http://www.ptgin.pl/zalecenie-sekcji-ultrasonografii-ptgip-w-zakresie-badan-usg-w-sytuacji-epidemiologicznej-covid-19.
  49. Coronavirus (COVID - 19) Infection in Pregnancy. RCOG. https://www.rcog.org.uk/globalassets/documents/guidelines/2020-06-18-coronavirus-covid-19-infection-in-pregnancy.pdf.
  50. Najnowsze wytyczne i stanowisko ekspertów w sprawie zakażenia wirusem COVID-19. http://ptmp.edu.pl/najnowsze-wytyczne-i-stanowisko-ekspertow-w-sprawie-zakazenia-wirusem-covid-19.
  51. Morau E, Bouvet L, Keita H, et al. CARO Working Group. Anaesthesia and intensive care in obstetrics during the COVID-19 pandemic. Anaesth Crit Care Pain Med. 2020; 39(3): 345–349.
  52. Wang L, Shi Y, Xiao T, et al. Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition). Annals of Translational Medicine. 2020; 8(3): 47–47.
  53. Poon LC, Yang H, Lee J, et al. ISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals. Ultrasound Obstet Gynecol. 2020; 55(5): 700–708.
  54. Martins-Filho PR, Santos VS, Santos HP. To breastfeed or not to breastfeed? Lack of evidence on the presence of SARS-CoV-2 in breastmilk of pregnant women with COVID-19. Rev Panam Salud Publica. 2020; 44: e59.
  55. Rasmussen SA, Smulian JC, Lednicky JA, et al. Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol. 2020; 222(5): 415–426.
  56. https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/pregnancy-breastfeeding.html#breastfeeding.
  57. Guan WJ, Ni ZY, Hu Yu, et al. China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18): 1708–1720.

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