open access

Vol 91, No 4 (2020)
ORIGINAL PAPERS Gynecology
Published online: 2020-04-29
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Increased risk of endometriosis in patients with endometritis — a nationwide cohort study involving 84,150 individuals

Kent Yu-Hsien Lin, Cherry Yin-Yi Chang, Wu-Chou Lin, Lei Wan
DOI: 10.5603/GP.2020.0040
·
Pubmed: 32374019
·
Ginekol Pol 2020;91(4):193-200.

open access

Vol 91, No 4 (2020)
ORIGINAL PAPERS Gynecology
Published online: 2020-04-29

Abstract

Objectives: To evaluate the incidence of endometriosis among endometritis patients and its association with confounding
comorbidities.
Material and methods: A population-based, retrospective cohort study of women aged between 20 to 55 years, who were
newly diagnosed with endometritis between 2000 to 2013. A total of 16,830 endometritis patients and 67,230 non-endometritis
individuals were enrolled by accessing data from the National Health Insurance Research Database of Taiwan.
The comorbidities accessed were uterine leiomyoma, rheumatoid arthritis, ovarian cancer, infertility and allergic diseases.
Results: The mean follow-up period was 9.15 years for the non-endometritis cohort and 9.13 years for the endometritis
cohort. There were significantly higher percentages of uterine leiomyoma, rheumatoid arthritis, infertility, ovarian cancer
and allergic diseases in the endometritis cohort than in the non-endometritis cohort. Patients with endometritis had
a 1.5-fold increased risk of their condition advancing to endometriosis (HR 1.58, 95% CI 1.48–1.68).
Conclusions: Our results suggest that patients with endometritis exhibited a positive correlation in developing endometriosis.

Abstract

Objectives: To evaluate the incidence of endometriosis among endometritis patients and its association with confounding
comorbidities.
Material and methods: A population-based, retrospective cohort study of women aged between 20 to 55 years, who were
newly diagnosed with endometritis between 2000 to 2013. A total of 16,830 endometritis patients and 67,230 non-endometritis
individuals were enrolled by accessing data from the National Health Insurance Research Database of Taiwan.
The comorbidities accessed were uterine leiomyoma, rheumatoid arthritis, ovarian cancer, infertility and allergic diseases.
Results: The mean follow-up period was 9.15 years for the non-endometritis cohort and 9.13 years for the endometritis
cohort. There were significantly higher percentages of uterine leiomyoma, rheumatoid arthritis, infertility, ovarian cancer
and allergic diseases in the endometritis cohort than in the non-endometritis cohort. Patients with endometritis had
a 1.5-fold increased risk of their condition advancing to endometriosis (HR 1.58, 95% CI 1.48–1.68).
Conclusions: Our results suggest that patients with endometritis exhibited a positive correlation in developing endometriosis.

Get Citation

Keywords

endometritis; inflammation; microbial infection; endometriosis

About this article
Title

Increased risk of endometriosis in patients with endometritis — a nationwide cohort study involving 84,150 individuals

Journal

Ginekologia Polska

Issue

Vol 91, No 4 (2020)

Pages

193-200

Published online

2020-04-29

DOI

10.5603/GP.2020.0040

Pubmed

32374019

Bibliographic record

Ginekol Pol 2020;91(4):193-200.

Keywords

endometritis
inflammation
microbial infection
endometriosis

Authors

Kent Yu-Hsien Lin
Cherry Yin-Yi Chang
Wu-Chou Lin
Lei Wan

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