open access

Vol 90, No 2 (2019)
ORIGINAL PAPERS Obstetrics
Published online: 2019-02-28
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Follow-up of children with antenatally diagnosed idiopathic polyhydramnios

Magdalena Adamczyk, Jakub Kornacki, Przemyslaw Wirstlein, Malgorzata Szczepanska, Ewa Wender-Ozegowska
DOI: 10.5603/GP.2019.0016
·
Pubmed: 30860276
·
Ginekol Pol 2019;90(2):93-99.

open access

Vol 90, No 2 (2019)
ORIGINAL PAPERS Obstetrics
Published online: 2019-02-28

Abstract

Objectives: The aim of our work was to assess the development of children with antenatally diagnosed idiopathic poly- hydramnios, over 12 months from the end of pregnancy. 

Material and methods: The study included 91 healthy pregnant patients with idiopathic polyhydramnios. Diagnostic tests results and perinatal medical history were obtained retrospectively. Parents of children were contacted by phone and by mail. The answers were obtained from 64 (70%) parents. For statistical analysis SigmaStat3.5 software was used. 

Results: Ninety six percent of parents declared that in their opinion the development of children was normal. Abnormali- ties were found in 44% of the children. Thirty percent of neonates demonstrated mild abnormalities which may be due to organic or functional neuromuscular disorders: abnormal muscle tone, speech apparatus and development disorders, swallowing and breathing problems (manifested as vomiting, excessive regurgitation, idiopathic apnoeas). 

Isolated small malformations were diagnosed in 12 (19%) children. Two children (3%) with SGA were diagnosed with genetic syndromes. More than one of the abnormalities described above were diagnosed in 14% of children. Gestational age at the time of polyhydramnios diagnosis and its severity were not prognostic factors for abnormalities. Seventy percent of newborns were male. 

Conclusions: Despite the subjectively positive assessment of the development of children by the majority of parents, groups of common disorders requiring long-term follow-up have been identified. Functional disorders of the gastrointestinal tract, CNS and the group of neuromuscular disorders may be responsible for idiopathic polyhydramnios. SGA with co-existing idiopathic polyhydramnios is associated with the risk of genetic diseases. The more frequent incidence of idiopathic poly- hydramnios in male fetuses requires further research. 

Abstract

Objectives: The aim of our work was to assess the development of children with antenatally diagnosed idiopathic poly- hydramnios, over 12 months from the end of pregnancy. 

Material and methods: The study included 91 healthy pregnant patients with idiopathic polyhydramnios. Diagnostic tests results and perinatal medical history were obtained retrospectively. Parents of children were contacted by phone and by mail. The answers were obtained from 64 (70%) parents. For statistical analysis SigmaStat3.5 software was used. 

Results: Ninety six percent of parents declared that in their opinion the development of children was normal. Abnormali- ties were found in 44% of the children. Thirty percent of neonates demonstrated mild abnormalities which may be due to organic or functional neuromuscular disorders: abnormal muscle tone, speech apparatus and development disorders, swallowing and breathing problems (manifested as vomiting, excessive regurgitation, idiopathic apnoeas). 

Isolated small malformations were diagnosed in 12 (19%) children. Two children (3%) with SGA were diagnosed with genetic syndromes. More than one of the abnormalities described above were diagnosed in 14% of children. Gestational age at the time of polyhydramnios diagnosis and its severity were not prognostic factors for abnormalities. Seventy percent of newborns were male. 

Conclusions: Despite the subjectively positive assessment of the development of children by the majority of parents, groups of common disorders requiring long-term follow-up have been identified. Functional disorders of the gastrointestinal tract, CNS and the group of neuromuscular disorders may be responsible for idiopathic polyhydramnios. SGA with co-existing idiopathic polyhydramnios is associated with the risk of genetic diseases. The more frequent incidence of idiopathic poly- hydramnios in male fetuses requires further research. 

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Keywords

congenital anomalies; development; functional disorders; idiopathic polyhydramnios; neuromuscular disorders

About this article
Title

Follow-up of children with antenatally diagnosed idiopathic polyhydramnios

Journal

Ginekologia Polska

Issue

Vol 90, No 2 (2019)

Pages

93-99

Published online

2019-02-28

DOI

10.5603/GP.2019.0016

Pubmed

30860276

Bibliographic record

Ginekol Pol 2019;90(2):93-99.

Keywords

congenital anomalies
development
functional disorders
idiopathic polyhydramnios
neuromuscular disorders

Authors

Magdalena Adamczyk
Jakub Kornacki
Przemyslaw Wirstlein
Malgorzata Szczepanska
Ewa Wender-Ozegowska

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