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Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients
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Abstract
Objectives: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.
Material and methods: We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative 18F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.
Results: The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III–IV compared with stage I–II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.
Conclusions: PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.
Abstract
Objectives: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.
Material and methods: We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative 18F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.
Results: The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III–IV compared with stage I–II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.
Conclusions: PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.
Keywords
PET/CT, endometrial cancer, prognosis, SUVmax
About this articleTitle
Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients
Journal
Issue
Article type
Research paper
Pages
493-497
Published online
2016-07-29
Page views
1308
Article views/downloads
1621
DOI
Pubmed
Bibliographic record
Ginekol Pol 2016;87(7):493-497.
Keywords
PET/CT
endometrial cancer
prognosis
SUVmax
Authors
Emre Özgü
Murat Öz
Yunus Yıldız
Burçin Salman Özgü
Salim Erkaya
Tayfun Güngör
