open access

Vol 87, No 5 (2016)
Research paper
Published online: 2016-06-02
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The association between placenta previa and leukocyte and platelet indices — a case control study

Ali O. Ersoy, Sibel Ozler, Efser Oztas, Ebru Ersoy, Ayse Kirbas, Nuri Danisman
·
Pubmed: 27304653
·
Ginekol Pol 2016;87(5):367-371.

open access

Vol 87, No 5 (2016)
ORIGINAL PAPERS Obstetrics
Published online: 2016-06-02

Abstract

Objectives: Despite medical advances, rising awareness, and satisfactory care facilities, placenta previa (PP) remains a challenging clinical entity due to the risk of excessive obstetric hemorrhage. Etiological concerns gave way to life-saving concerns about the prediction of maternal outcomes due to hemorrhage. Our study aimed to detect an early predictive marker of placenta previa.

Material and methods: Ninety-three pregnant patients diagnosed with PP and 247 controls were recruited for this retro­spective study. Platelet and leukocyte indices were compared between the two groups.

Results: The groups were similar with regard to age distribution (31.2 ± 5.1 years [mean ± SD] in the PP group and 31.7 ± 4.2 years in controls), body mass index (BMI) (27.7 ± 3.6 kg/m2 in the PP group and 27.4 ± 4.6 kg/m2 in controls), and most characteristics of the obstetric history. Total leukocyte count, neutrophil count, and neutrophil-to-lymphocyte ratio were significantly higher in the PP group. Mean platelet volume (MPV) and large platelet cell ratio (P-LCR) values were significantly lower in the PP group as compared to controls, with regard to third trimester values. However, patients who were diagnosed postnatally with placenta percreta had lower MPV and P-LCR values than other patients with PP. There were no statistically significant differences between the two groups as far as first trimester values were concerned.

Conclusions: Platelet and leukocyte indices in the third trimester of pregnancy may be valuable predictors of placenta previa and placenta percreta. More comprehensive studies are needed to address this issue.

Abstract

Objectives: Despite medical advances, rising awareness, and satisfactory care facilities, placenta previa (PP) remains a challenging clinical entity due to the risk of excessive obstetric hemorrhage. Etiological concerns gave way to life-saving concerns about the prediction of maternal outcomes due to hemorrhage. Our study aimed to detect an early predictive marker of placenta previa.

Material and methods: Ninety-three pregnant patients diagnosed with PP and 247 controls were recruited for this retro­spective study. Platelet and leukocyte indices were compared between the two groups.

Results: The groups were similar with regard to age distribution (31.2 ± 5.1 years [mean ± SD] in the PP group and 31.7 ± 4.2 years in controls), body mass index (BMI) (27.7 ± 3.6 kg/m2 in the PP group and 27.4 ± 4.6 kg/m2 in controls), and most characteristics of the obstetric history. Total leukocyte count, neutrophil count, and neutrophil-to-lymphocyte ratio were significantly higher in the PP group. Mean platelet volume (MPV) and large platelet cell ratio (P-LCR) values were significantly lower in the PP group as compared to controls, with regard to third trimester values. However, patients who were diagnosed postnatally with placenta percreta had lower MPV and P-LCR values than other patients with PP. There were no statistically significant differences between the two groups as far as first trimester values were concerned.

Conclusions: Platelet and leukocyte indices in the third trimester of pregnancy may be valuable predictors of placenta previa and placenta percreta. More comprehensive studies are needed to address this issue.

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Keywords

prediction, placenta previa, placenta percreta, platelet indices, leukocyte indices

About this article
Title

The association between placenta previa and leukocyte and platelet indices — a case control study

Journal

Ginekologia Polska

Issue

Vol 87, No 5 (2016)

Article type

Research paper

Pages

367-371

Published online

2016-06-02

Page views

1885

Article views/downloads

1748

DOI

10.5603/GP.2016.0006

Pubmed

27304653

Bibliographic record

Ginekol Pol 2016;87(5):367-371.

Keywords

prediction
placenta previa
placenta percreta
platelet indices
leukocyte indices

Authors

Ali O. Ersoy
Sibel Ozler
Efser Oztas
Ebru Ersoy
Ayse Kirbas
Nuri Danisman

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