Vol 95, No 6 (2024)
Research paper
Published online: 2023-10-06

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Neonatal outcomes for women diagnosed with cancer during pregnancy — single-center study

Beata Pawlus12, Jerzy Zwolinski12, Urszula Koneczna12, Grzegorz Pawlus3, Agnieszka Kordek4
Pubmed: 37801621
Ginekol Pol 2024;95(6):443-450.

Abstract

Objectives: Pregnancy complicated by cancer is one of the most serious challenges of modern perinatology. The increasing number of cancers diagnosed and treated during pregnancy requires a multidisciplinary approach to optimize the treatment of the person who is pregnant and deliver a healthy child. The aim of the study is to analyze the course of
the neonatal period in children of mothers suffering from cancer during pregnancy, treated in a specialist hospital for
women and children for ten years.
Material and methods: Retrospective observational study. Being diagnosed with cancer during pregnancy significantly
increases the risk of premature delivery, prematurity and intrauterine growth restriction.
Results: Our own observations show no significant differences in the course of the neonatal period in children of mothers
suffering from a malignant tumor during pregnancy compared to children of healthy mothers. This applies to both
full-term and premature babies.
Conclusions: Modern treatment of malignant tumors during pregnancy seems to be safe for the fetus and newborn. It
is optimal to conduct oncological, obstetric and neonatological treatment in one center. It seems advisable to conduct
long-term follow-up observations in children of pregnant people with cancer. Since the described groups of patients and
their newborns are small and heterogeneous, in order to develop appropriate standards, it is recommended to report
these cases to central registers.

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