open access

Vol 91, No 12 (2020)
Clinical vignette
Published online: 2020-11-24
Get Citation

Placental mesenchymal dysplasia and hepatic cyst

Anna Rosner-Tenerowicz1, Michal Pomorski1, Tomasz Fuchs1, Jakub Sliwa1, Aleksandra Zimmer-Stelmach1, Wiktor Bek1, Mariusz Zimmer1
DOI: 10.5603/GP.a2020.0129
·
Pubmed: 33448000
·
Ginekol Pol 2020;91(12):779-780.
Affiliations
  1. 2nd Department of Gynecology and Obstetrics, Wroclaw Medical University, Wroclaw, Poland

open access

Vol 91, No 12 (2020)
CLINICAL VIGNETTES
Published online: 2020-11-24

Abstract

Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as
a molar pregnancy resulting in unnecessary termination of pregnancy.
A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound
showed a bulky placenta with multiple cysts. Oligohydramnion and fetal hypoechogenic cystic area without doppler flow
were diagnosed at 23 weeks. The baby was operated on after delivery, and an 80 mm multifocal cyst originating from the right
lobe of the liver was removed. The placenta demonstrated swelling stem villi with enlarged vessels and increased interstitial
cells without trophoblast proliferation. PMD and fetal hepatic cyst can coexist; however, the relationship between those
conditions remains to be elucidated. PMD is associated with adverse pregnancy outcomes but also with a good prognosis.

Abstract

Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as
a molar pregnancy resulting in unnecessary termination of pregnancy.
A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound
showed a bulky placenta with multiple cysts. Oligohydramnion and fetal hypoechogenic cystic area without doppler flow
were diagnosed at 23 weeks. The baby was operated on after delivery, and an 80 mm multifocal cyst originating from the right
lobe of the liver was removed. The placenta demonstrated swelling stem villi with enlarged vessels and increased interstitial
cells without trophoblast proliferation. PMD and fetal hepatic cyst can coexist; however, the relationship between those
conditions remains to be elucidated. PMD is associated with adverse pregnancy outcomes but also with a good prognosis.

Get Citation

Keywords

placental mesenchymal dysplasia; hepatic cyst

About this article
Title

Placental mesenchymal dysplasia and hepatic cyst

Journal

Ginekologia Polska

Issue

Vol 91, No 12 (2020)

Article type

Clinical vignette

Pages

779-780

Published online

2020-11-24

DOI

10.5603/GP.a2020.0129

Pubmed

33448000

Bibliographic record

Ginekol Pol 2020;91(12):779-780.

Keywords

placental mesenchymal dysplasia
hepatic cyst

Authors

Anna Rosner-Tenerowicz
Michal Pomorski
Tomasz Fuchs
Jakub Sliwa
Aleksandra Zimmer-Stelmach
Wiktor Bek
Mariusz Zimmer

References (4)
  1. Arizawa M, Nakayama M. Suspected involvement of the X chromosome in placental mesenchymal dysplasia. Congenit Anom (Kyoto). 2002; 42(4): 309–317.
  2. Thompson JMD, Irgens LM, Skjaerven R, et al. Placenta weight percentile curves for singleton deliveries. BJOG. 2007; 114(6): 715–720.
  3. Nayeri UA, West AB, Grossetta Nardini HK, et al. Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 2013; 41(4): 366–374.
  4. H'mida D, Gribaa M, Yacoubi T, et al. Placental mesenchymal dysplasia with beckwith-wiedemann syndrome fetus in the context of biparental and androgenic cell lines. Placenta. 2008; 29(5): 454–460.

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