Vol 91, No 7 (2020)
Review paper
Published online: 2020-07-31

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The role of diet and probiotics in prevention and treatment of bacterial vaginosis and vulvovaginal candidiasis in adolescent girls and non-pregnant women

Malgorzata Mizgier1, Grazyna Jarzabek-Bielecka2, Kinga Mruczyk1, Witold Kedzia3
Pubmed: 32779162
Ginekol Pol 2020;91(7):412-416.

Abstract

The article raises important issues regarding the use of diet and probiotics in prevention and treatment of vaginitis.
Vaginitis is defined as any condition with symptoms of abnormal vaginal discharge. The most common causes of vaginitis
are vulvovaginal candidiasis (VVC), trichomoniasis and bacterial vaginosis (BV). Vaginitis has been linked to itching, burning,
pain, discharge, irritation and also adverse reproductive and obstetric health outcomes. Moreover, microorganisms that
build vaginal flora in the state of bacterial vaginosis are a source of cervicitis and endometritis (often in subclinical forms)
and pelvic inflammatory disease (PID)
The proper diet and probiotics consumption may influence the composition of the gut microbiota, improve gut integrity,
and have an impact on maintaining and recovering the normal vaginal microbiota.
Future studies and reviews investigating the role of diet and probiotics in changes to gut and vaginal microbiome need to
focus on deciphering the mechanismus of host bacteria interaction in vulvovaginal health.

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References

  1. Jarząbek-Bielecka G, Pawlaczyk M, Pisarska-Krawczyk M, et al. The problem of inflammation of the female genital system - assessment of girls' knowledge about prevention and treatment. Med Rodz. 2018; 21(1A): 29–36.
  2. Paladine HL, Desai UA. Vaginitis: Diagnosis and Treatment. Am Fam Physician. 2018; 97(5): 321–329.
  3. Thoma ME, Klebanoff MA, Rovner AJ, et al. Bacterial vaginosis is associated with variation in dietary indices. J Nutr. 2011; 141(9): 1698–1704.
  4. Pawlaczyk M, Jarząbek G, Pawlaczyk M, et al. Vulvar disease, vulvovaginitis in adolescent girl. Ginek Prakt. 2006; 1(14): 116–118.
  5. Skłodowska A, Pawlaczyk M, Jarząbek G, et al. Aspekty kliniczne zapalenia sromu i pochwy u dziewczynek w wieku przedpokwitaniowym (Clinical aspects of vulvovaginitis in pre-pubertal girls). Przegl Derm. 2011; 1(98): 48–49.
  6. Jarząbek-Bielecka G, Pawlaczyk M, Pisarska-Krawczyk M. Zapalenia sromu i pochwy po menopauzie. In: Pisarska-Krawczyk M, Jarząbek-Bielecka G. ed. Zagadnienia interdyscyplinarne w ginekologii praktycznej. Wydawnictwo Uczelniane PWSZ, Kalisz 2014.
  7. Jarząbek-Bielecka G, Pawlaczyk M, Pisarska-Krawczyk M, et al. Sexually transmitted diseases in adolescents. Current Gynecologic Oncology. 2015; 13(1): 20–26.
  8. Jarząbek-Bielecka G. Srebro TIAB a zapalenia i zakażenia narządów płciowych, ze szczególnym uwzględnieniem pacjentek w wieku rozwojowym (TIAB silver and genital inflammation and infections, with a special focus on patients in developmentalal age). Anal Przypadków Ginek Położ. 2017; 1(18): 20–22.
  9. Sobel J. Vulvovaginal candidosis. The Lancet. 2007; 369(9577): 1961–1971.
  10. Jagodzinski A, Zielinska E, Laczmanski L, et al. The early years of life. Are they influenced by our microbiome? Ginekol Pol. 2019; 90(4): 228–232.
  11. Statement of the Polish Gynecological Society Expert Group on the use of ellen. Ginekol Pol. 2012; 83(8): 633–638.
  12. Dankovich N. New opportunities in preparation of women with reproductive tracts microbiocenosis disorder for gynaecologic intervention. Women Health. 2006; 2: 1–6.
  13. Leeming ER, Johnson AJ, Spector TD, et al. Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration. Nutrients. 2019; 11(12).
  14. Parsapure R, Rahimiforushani A, Majlessi F, et al. Impact of Health-Promoting Educational Intervention on Lifestyle (Nutrition Behaviors, Physical Activity and Mental Health) Related to Vaginal Health Among Reproductive-Aged Women With Vaginitis. Iran Red Crescent Med J. 2016; 18(10): e37698.
  15. Al-Ghazzewi FH, Tester RF. Biotherapeutic agents and vaginal health. J Appl Microbiol. 2016; 121(1): 18–27.
  16. Neggers Y, Nansel T, Andrews W, et al. Dietary Intake of Selected Nutrients Affects Bacterial Vaginosis in Women. J Nutr. 2007; 137(9): 2128–2133.
  17. Tilg H. Obesity, metabolic syndrome, and microbiota: multiple interactions. J Clin Gastroenterol. 2010; 44 Suppl 1: S16–S18.
  18. Neggers YH, Nansel TR, Andrews WW, et al. Dietary intake of selected nutrients affects bacterial vaginosis in women. J Nutr. 2007; 137(9): 2128–2133.
  19. Westney OE, Westney LS, Johnson AA, et al. Nutrition, genital tract infections, hematologic values, and premature rupture of membranes among African American women. J Nutr. 1994; 124: S987–S993.
  20. Antonio MAD, Rabe LK, Hillier SL. Colonization of the rectum by Lactobacillus species and decreased risk of bacterial vaginosis. J Infect Dis. 2005; 192(3): 394–398.
  21. Tuddenham S, Ghanem KG, Caulfield LE, et al. Associations between dietary micronutrient intake and molecular-Bacterial Vaginosis. Reprod Health. 2019; 16(1): 151.
  22. Report of a joint FAO/WHO expert consultation on evaluation of health and nutritional properties of probiotics in food including powder milk and live lactic acid bacteria [Internet]. Cordoba, Argentina: Food and Agriculture Organisation (FAO)/World Health organisation (WHO). 2001. http://www.fao.org/3/a-a0512e.pdf (2.01.2018).
  23. Jarde A, Lewis-Mikhael AM, Moayyedi P, et al. Pregnancy outcomes in women taking probiotics or prebiotics: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2018; 18(1): 14.
  24. Buggio L, Somigliana E, Borghi A, et al. Probiotics and vaginal microecology: fact or fancy? BMC Womens Health. 2019; 19(1): 25.
  25. Bastani P, Homayouni A, Gasemnezhad V, et al. Dairy Probiotic Foods and Bacterial Vaginosis: A Review on Mechanism of Action. Probiotics. 2012.
  26. Ford AC, Quigley EMM, Lacy BE, et al. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol. 2014; 109(10): 1547–61; quiz 1546, 1562.
  27. Goldenberg J, Yap C, Lytvyn L, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev. 2017.
  28. Ma L, Su J, Su Y, et al. Probiotics administered intravaginally as a complementary therapy combined with antibiotics for the treatment of bacterial vaginosis: a systematic review protocol. BMJ Open. 2017; 7(10): e019301.
  29. Reid G, Younes JA, Van der Mei HC, et al. Microbiota restoration: natural and supplemented recovery of human microbial communities. Nat Rev Microbiol. 2011; 9(1): 27–38.
  30. Xie HYu, Feng D, Wei DM, et al. Probiotics for vulvovaginal candidiasis in non-pregnant women. Cochrane Database Syst Rev. 2017; 11: CD010496.
  31. So D, Whelan K, Rossi M, et al. Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis. Am J Clin Nutr. 2018; 107(6): 965–983.