open access

Vol 91, No 9 (2020)
Research paper
Published online: 2020-09-23
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Are neutrophil to lymphocyte ratio and platelet to lymphocyte ratio clinically useful for the prediction of early pregnancy loss?

Süleyman Cemil Oğlak1, Mustafa Fırat Aydın1
DOI: 10.5603/GP.a2020.0082
·
Pubmed: 33030732
·
Ginekol Pol 2020;91(9):524-527.
Affiliations
  1. Department of Gynecology and Obstetrics, Health Sciences University, Gazi Yasargil Training and Research Hospital, Diyarbakır, Turkey

open access

Vol 91, No 9 (2020)
ORIGINAL PAPERS Obstetrics
Published online: 2020-09-23

Abstract

Objectives: Red cell distribution width (RDW), mean platelet volume (MPV), plateletcrit (PCT), platelet distribution width (PDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have all been identified as systemic inflammatory markers. The aim of this study to investigate whether the use of systemic inflammatory markers can predict early pregnancy loss.
Material and methods: A total of 137 patients with early pregnancy loss was compared with 148 participants in the control group who had given birth at term. In the study group, CBC values were included in the study at the time of referral to the hospital for routine follow-up, while patients did not experience early pregnancy loss. In the control group, CBC values of the patient before the seventh week of pregnancy were included in the study.
Results: There was no significant difference between the two groups in terms of RDW, MPV, PCT and PDW values. The NLR and PLR values were significantly higher in the early pregnancy loss group than the control group (p < 0.05).
Conclusion: Our findings suggest that high NLR and PLR values are potent markers for the prediction of early pregnancy loss.

Abstract

Objectives: Red cell distribution width (RDW), mean platelet volume (MPV), plateletcrit (PCT), platelet distribution width (PDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have all been identified as systemic inflammatory markers. The aim of this study to investigate whether the use of systemic inflammatory markers can predict early pregnancy loss.
Material and methods: A total of 137 patients with early pregnancy loss was compared with 148 participants in the control group who had given birth at term. In the study group, CBC values were included in the study at the time of referral to the hospital for routine follow-up, while patients did not experience early pregnancy loss. In the control group, CBC values of the patient before the seventh week of pregnancy were included in the study.
Results: There was no significant difference between the two groups in terms of RDW, MPV, PCT and PDW values. The NLR and PLR values were significantly higher in the early pregnancy loss group than the control group (p < 0.05).
Conclusion: Our findings suggest that high NLR and PLR values are potent markers for the prediction of early pregnancy loss.

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Keywords

early pregnancy loss; systemic inflammation; inflammatory markers

About this article
Title

Are neutrophil to lymphocyte ratio and platelet to lymphocyte ratio clinically useful for the prediction of early pregnancy loss?

Journal

Ginekologia Polska

Issue

Vol 91, No 9 (2020)

Article type

Research paper

Pages

524-527

Published online

2020-09-23

DOI

10.5603/GP.a2020.0082

Pubmed

33030732

Bibliographic record

Ginekol Pol 2020;91(9):524-527.

Keywords

early pregnancy loss
systemic inflammation
inflammatory markers

Authors

Süleyman Cemil Oğlak
Mustafa Fırat Aydın

References (25)
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