open access

Vol 87, No 7 (2016)
Research paper
Published online: 2016-07-29
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Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients

Emre Özgü, Murat Öz, Yunus Yıldız, Burçin Salman Özgü, Salim Erkaya, Tayfun Güngör
DOI: 10.5603/GP.2016.0032
·
Pubmed: 27504941
·
Ginekol Pol 2016;87(7):493-497.

open access

Vol 87, No 7 (2016)
ORIGINAL PAPERS Gynecology
Published online: 2016-07-29

Abstract

Objectives: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.

Material and methods: We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative 18F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.

Results: The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III–IV compared with stage I–II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.

Conclusions: PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.

Abstract

Objectives: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.

Material and methods: We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative 18F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.

Results: The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III–IV compared with stage I–II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.

Conclusions: PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.

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Keywords

PET/CT, endometrial cancer, prognosis, SUVmax

About this article
Title

Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients

Journal

Ginekologia Polska

Issue

Vol 87, No 7 (2016)

Article type

Research paper

Pages

493-497

Published online

2016-07-29

DOI

10.5603/GP.2016.0032

Pubmed

27504941

Bibliographic record

Ginekol Pol 2016;87(7):493-497.

Keywords

PET/CT
endometrial cancer
prognosis
SUVmax

Authors

Emre Özgü
Murat Öz
Yunus Yıldız
Burçin Salman Özgü
Salim Erkaya
Tayfun Güngör

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