open access

Vol 87, No 4 (2016)
REVIEW PAPERS Obstetrics
Published online: 2016-05-23
Get Citation

Pharmacotherapeutic aspects of drug transporters in the placenta

Olga Motyl, Marek Droździk
DOI: 10.17772/gp/61558
·
Pubmed: 27321104
·
Ginekol Pol 2016;87(4):305-309.

open access

Vol 87, No 4 (2016)
REVIEW PAPERS Obstetrics
Published online: 2016-05-23

Abstract

Drug treatment during pregnancy is often inevitable. The number of pregnant women in need of pharmacotherapy continues to grow, partly due to advanced diagnostic tests and partly due to advanced maternal age. Obviously, knowledge about the function of drug transporters in the placenta allows for a more accurate analysis of drug penetration (and other xenobiotics) through the placental barrier, and therefore safer pharmacotherapy. The paper provides information on the role of drug transporters in the pharmacotherapy of pregnancy-associated pathologies which require long-term treatment, e.g. cardiac arrhythmias, gestational diabetes, epilepsy, HIV infection, preeclampsia, and conditions which require the use of glucocorticoids.

Abstract

Drug treatment during pregnancy is often inevitable. The number of pregnant women in need of pharmacotherapy continues to grow, partly due to advanced diagnostic tests and partly due to advanced maternal age. Obviously, knowledge about the function of drug transporters in the placenta allows for a more accurate analysis of drug penetration (and other xenobiotics) through the placental barrier, and therefore safer pharmacotherapy. The paper provides information on the role of drug transporters in the pharmacotherapy of pregnancy-associated pathologies which require long-term treatment, e.g. cardiac arrhythmias, gestational diabetes, epilepsy, HIV infection, preeclampsia, and conditions which require the use of glucocorticoids.

Get Citation

Keywords

drug transporters; placenta; pharmacotherapy

About this article
Title

Pharmacotherapeutic aspects of drug transporters in the placenta

Journal

Ginekologia Polska

Issue

Vol 87, No 4 (2016)

Pages

305-309

Published online

2016-05-23

DOI

10.17772/gp/61558

Pubmed

27321104

Bibliographic record

Ginekol Pol 2016;87(4):305-309.

Keywords

drug transporters
placenta
pharmacotherapy

Authors

Olga Motyl
Marek Droździk

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