Vol 78, No 5 (2007)

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The efficacy of SUI treatment with Burch colposuspension evaluated with use of ITT analysis

Grzegorz Surkont, Edyta Wlaźlak, Aldona Dunicz-Sokołowska, Jacek Suzin
Ginekol Pol 2007;78(5).


Objectives: Search for methods of assessment of effects of SUI treatment, which goal is to minimize risk of bias, are inconclusive and remain the subject of investigation. Design: The aim of the study was to analyze the influence of application of different methods of efficacy measurement of SUI treatment with use of Burch colposuspension on final conclusions concerning the treatment effects. Material and methods: Prospective investigation was carried out among 50 women with SUI symptoms II or III degree, scheduled for Burch colposuspension. The analysis of obtained results was carried out with use of ITT and modified ITT. To compare, therapy effects were explored with the use of principles which have been, until quite recently, most often used in urogynecology. Results: Differences in percentage of cured, based on results of several urogynecologic examinations according to method of analysis (previously used method, ITT, modified ITT), have oscillated between 3% to 20%. Conclusions: 1. While selecting diagnostic methods to analyze SUI treatment effectiveness, potential problems with obtaining complete data after the treatment should be taken into account. 2. In order to minimize statistic bias, the usage of few methods of analysis of obtained results is highly recommended.

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