Vol 78, No 8 (2007)

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Leptin, leptin gene, leptin gene receptor polymorphisms and pregnancy

Rafał Iciek, Ewa Wender-Ożegowska, Agnieszka Seremak-Mrozikiewicz, Krzysztof Drews, Jacek Brązert
Ginekol Pol 2007;78(8).


The article presents information about leptin as the major metabolic hormone. The structure, localization of the hormone and its receptor have been described focusing on maturation and fertility processes. Several polymorphisms of leptin gene and its receptor have been described as potential developmental factors of pregnancy complications such as diabetes mellitus or pregnancy induced hypertension.

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