open access

Vol 78, No 9 (2007)
ARTICLES
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Tumor makers in cervical cancer

Janina Markowska
Ginekol Pol 2007;78(9).

open access

Vol 78, No 9 (2007)
ARTICLES

Abstract

Measurement of tumor markers level in human body fluids, mainly in serum may be useful for diagnosis, therapy monitoring and early recurrence detection. SCC-Ag, Cyfra 21-1, CEA, CA 125 and TPS are of a clinical value in uterine cervical cancer despite their diverse significance. Other biological markers that could be measured in serum as well as in tumor tissue are cytokines: VEGF, IL-6, IL-8, IL-4, IL-10, leptin, stromal drive factor (SDF-1), although assessment of their importance needs further examination. Elevation of uterine cervical cancer hypoxia markers such as HIF 1a, CA 9, GLUT- 1 is combined with poorer clinical outcome prognosis.

Abstract

Measurement of tumor markers level in human body fluids, mainly in serum may be useful for diagnosis, therapy monitoring and early recurrence detection. SCC-Ag, Cyfra 21-1, CEA, CA 125 and TPS are of a clinical value in uterine cervical cancer despite their diverse significance. Other biological markers that could be measured in serum as well as in tumor tissue are cytokines: VEGF, IL-6, IL-8, IL-4, IL-10, leptin, stromal drive factor (SDF-1), although assessment of their importance needs further examination. Elevation of uterine cervical cancer hypoxia markers such as HIF 1a, CA 9, GLUT- 1 is combined with poorer clinical outcome prognosis.
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Keywords

tantigenes neoplasms - analysis, tumor markers biological - analysis, tumor markers biological - blood, uterine cervical neoplasms

About this article
Title

Tumor makers in cervical cancer

Journal

Ginekologia Polska

Issue

Vol 78, No 9 (2007)

Bibliographic record

Ginekol Pol 2007;78(9).

Keywords

tantigenes neoplasms - analysis
tumor markers biological - analysis
tumor markers biological - blood
uterine cervical neoplasms

Authors

Janina Markowska

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