Vol 78, No 10 (2007)
ARTICLES
Concentration of TNF-alpha in the postoperative period in patients with benign adnexal tumors treated by laparoscopy or laparotomy
Anna Torres, Kamil Torres, Tomasz Paszkowski, Grzegorz Staśkiewicz, Ryszard Maciejewski, Ewa Woźniakowska, Wacława Zaleska
Vol 78, No 10 (2007)
ARTICLES
Abstract
OBJECTIVES: The aim of the study was to compare serum concentrations of the TNF-alpha (TNF-alpha) in the early postoperative period in patients with benign adnexal masses operated by laparoscopy or laparotomy. MATERIAL AND METHODS: The study was conducted in a group of patients aged from 20 to 52, operated due to adnexal masses. Out of 40 patients included in the study, 25 underwent laparoscopy and 15 underwent laparotomy. Serum concentrations of TNF-alpha were measured by commercially available ELISA assays before the surgery and 4, 24 and 48 hours after the start of the operation. RESULTS: A decrease of TNF-alpha serum concentrations was observed in the early postoperative period. 24 h after the operation concentrations of TNF-alpha were significantly higher in the laparotomy group as opposed to the group operated by laparoscopy. CONCLUSIONS: Lower concentrations of TNF-alpha in the laparoscopy group, observed 24 hours after the operation, may reflect more favorable changes in the systemic inflammatory response after minimally invasive management of benign ovarian masses.
Abstract
OBJECTIVES: The aim of the study was to compare serum concentrations of the TNF-alpha (TNF-alpha) in the early postoperative period in patients with benign adnexal masses operated by laparoscopy or laparotomy. MATERIAL AND METHODS: The study was conducted in a group of patients aged from 20 to 52, operated due to adnexal masses. Out of 40 patients included in the study, 25 underwent laparoscopy and 15 underwent laparotomy. Serum concentrations of TNF-alpha were measured by commercially available ELISA assays before the surgery and 4, 24 and 48 hours after the start of the operation. RESULTS: A decrease of TNF-alpha serum concentrations was observed in the early postoperative period. 24 h after the operation concentrations of TNF-alpha were significantly higher in the laparotomy group as opposed to the group operated by laparoscopy. CONCLUSIONS: Lower concentrations of TNF-alpha in the laparoscopy group, observed 24 hours after the operation, may reflect more favorable changes in the systemic inflammatory response after minimally invasive management of benign ovarian masses.
Title
Concentration of TNF-alpha in the postoperative period in patients with benign adnexal tumors treated by laparoscopy or laparotomy
Journal
Ginekologia Polska
Issue
Vol 78, No 10 (2007)
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456
Bibliographic record
Ginekol Pol 2007;78(10).
Authors
Anna Torres
Kamil Torres
Tomasz Paszkowski
Grzegorz Staśkiewicz
Ryszard Maciejewski
Ewa Woźniakowska
Wacława Zaleska
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