open access

Vol 78, No 12 (2007)
ARTICLES
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New views on hyperplastic endometrial lesions classification – endometrial intraepithelial neoplasia (EIN)

Tomasz Pertyński, Marcin Wrona, Anna Sobczuk
Ginekol Pol 2007;78(12).

open access

Vol 78, No 12 (2007)
ARTICLES

Abstract

Abstract The aim of the study was to present a new EIN classification of premalignant endometrial lesions. The diagnosis of precancerous disease of the endometrium remains non-standardized because the most widely used World Health Organisation classification is a poorly reproducible system, which does not specify objective architectural criteria for each category of hyperplasia and does not correspond to an appropriate clinical management (undertreatment, overtreatment of the lesions). The new proposed EIN diagnostic schema, based on integrated morphological, genetic molecular, objective histomorphometric (D-score) and clinical outcome studies, divides endometrial lesions into three categories: benign hyperplasia, endometrial intraepithelial neoplasia, and cancer.

Abstract

Abstract The aim of the study was to present a new EIN classification of premalignant endometrial lesions. The diagnosis of precancerous disease of the endometrium remains non-standardized because the most widely used World Health Organisation classification is a poorly reproducible system, which does not specify objective architectural criteria for each category of hyperplasia and does not correspond to an appropriate clinical management (undertreatment, overtreatment of the lesions). The new proposed EIN diagnostic schema, based on integrated morphological, genetic molecular, objective histomorphometric (D-score) and clinical outcome studies, divides endometrial lesions into three categories: benign hyperplasia, endometrial intraepithelial neoplasia, and cancer.
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Keywords

endometrial intraepithelial neoplasia - EIN, endometrioioid neoplasia - EN, Endometrial Hyperplasia

About this article
Title

New views on hyperplastic endometrial lesions classification – endometrial intraepithelial neoplasia (EIN)

Journal

Ginekologia Polska

Issue

Vol 78, No 12 (2007)

Bibliographic record

Ginekol Pol 2007;78(12).

Keywords

endometrial intraepithelial neoplasia - EIN
endometrioioid neoplasia - EN
Endometrial Hyperplasia

Authors

Tomasz Pertyński
Marcin Wrona
Anna Sobczuk

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