open access

Vol 78, No 12 (2007)
ARTICLES
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DNA adducts in human female genital organs

Włodzimierz Baranowski, Marta Monist, Dorota Prządka-Rabaniuk
Ginekol Pol 2007;78(12).

open access

Vol 78, No 12 (2007)
ARTICLES

Abstract

Abstract DNA adducts, one of genetic damages markers, precede and finally can lead to oncogenic mutations. They appear in genome as a result of DNA bases damages caused by various and numerous environmental factors eg. ultraviolet light, ionic radiation, toxins and also endogenic substances, for example estrogens. It is believed that the creation of DNA adducts is a necessary but insufficient process for the neoplastic transformation of the cell. The following review presents concise knowledge about the DNA adducts creation and their sequels served in healthy and cancerous tissues of the female genital organs, on the base of the available data.

Abstract

Abstract DNA adducts, one of genetic damages markers, precede and finally can lead to oncogenic mutations. They appear in genome as a result of DNA bases damages caused by various and numerous environmental factors eg. ultraviolet light, ionic radiation, toxins and also endogenic substances, for example estrogens. It is believed that the creation of DNA adducts is a necessary but insufficient process for the neoplastic transformation of the cell. The following review presents concise knowledge about the DNA adducts creation and their sequels served in healthy and cancerous tissues of the female genital organs, on the base of the available data.
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Keywords

human female genital organs, DNA Adducts, endometrial cancer

About this article
Title

DNA adducts in human female genital organs

Journal

Ginekologia Polska

Issue

Vol 78, No 12 (2007)

Bibliographic record

Ginekol Pol 2007;78(12).

Keywords

human female genital organs
DNA Adducts
endometrial cancer

Authors

Włodzimierz Baranowski
Marta Monist
Dorota Prządka-Rabaniuk

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