Vol 79, No 4 (2008)
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Photodynamic therapy in vulvar intraepithelial neoplasia

Aleksander Sieroń, Sylwia Kellas-Ślęczka, Tomasz Biniszkiewicz, Iwona Kozak-Darmas, Anita Olejek
Ginekol Pol 2008;79(4).

Abstract

Abstract Introduction: Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN). Design: The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN). Material and methods: We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva. Conclusions: We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree.

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