Vol 79, No 6 (2008)
ARTICLES
Value of the intraoperative assessment of the depth of myometrial invasion in endometrial carcinoma
Dariusz Ulman, Piotr Król, Andrzej Skręt, Joanna Skręt-Margieło, Marzanna Obrzut, Bogdan Obrzut, Marcin Żmuda
Vol 79, No 6 (2008)
ARTICLES
Abstract
Abstract Objectives: The aim of the study was to evaluate the value of intraoperative assessment of depth of myometrial invasion in patients with FIGO stage I of the endometrial carcinoma. Material and methods: A total number of 112 patients with FIGO stage I of the endometrial carcinoma undergoing surgery were enrolled in the study. All patients had undergone intraoperative assessment of the depth of myometrial invasion performed by a surgeon. The depth was determined as more or less than 50% of myometrial thickness according to FIGO classification. Gross visual estimation of the depth of myometrial invasion at the time of the operation was compared with the final histopathological report. Sensitivity, specificity and positive and negative predictive values of the method were determined by means of statistical analyses. Results: The depth of the myometrial invasion was accurately determined by the surgeon in 82.1% of cases. Sensitivity and specificity were 68% and 82.1%, respectively. The accurate prediction rate of the myometrial invasion in the group of patients with well differentiated (G1) endometrial carcinoma was higher (88,4%) than in group with moderately and low differentiated tumour (78,3%). Conclusions: The accuracy of macroscopic evaluation of myometrial invasion is high and reaches up to 82,1%. The accurate determination rate increases if the differentiation of tumour is higher.
Abstract
Abstract Objectives: The aim of the study was to evaluate the value of intraoperative assessment of depth of myometrial invasion in patients with FIGO stage I of the endometrial carcinoma. Material and methods: A total number of 112 patients with FIGO stage I of the endometrial carcinoma undergoing surgery were enrolled in the study. All patients had undergone intraoperative assessment of the depth of myometrial invasion performed by a surgeon. The depth was determined as more or less than 50% of myometrial thickness according to FIGO classification. Gross visual estimation of the depth of myometrial invasion at the time of the operation was compared with the final histopathological report. Sensitivity, specificity and positive and negative predictive values of the method were determined by means of statistical analyses. Results: The depth of the myometrial invasion was accurately determined by the surgeon in 82.1% of cases. Sensitivity and specificity were 68% and 82.1%, respectively. The accurate prediction rate of the myometrial invasion in the group of patients with well differentiated (G1) endometrial carcinoma was higher (88,4%) than in group with moderately and low differentiated tumour (78,3%). Conclusions: The accuracy of macroscopic evaluation of myometrial invasion is high and reaches up to 82,1%. The accurate determination rate increases if the differentiation of tumour is higher.
Keywords
myometrium - invasion, endometrial carcinoma
Title
Value of the intraoperative assessment of the depth of myometrial invasion in endometrial carcinoma
Journal
Ginekologia Polska
Issue
Vol 79, No 6 (2008)
Page views
551
Article views/downloads
709
Bibliographic record
Ginekol Pol 2008;79(6).
Keywords
myometrium - invasion
endometrial carcinoma
Authors
Dariusz Ulman
Piotr Król
Andrzej Skręt
Joanna Skręt-Margieło
Marzanna Obrzut
Bogdan Obrzut
Marcin Żmuda
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