open access

Vol 79, No 6 (2008)
ARTICLES
Get Citation

Value of the intraoperative assessment of the depth of myometrial invasion in endometrial carcinoma

Dariusz Ulman, Piotr Król, Andrzej Skręt, Joanna Skręt-Margieło, Marzanna Obrzut, Bogdan Obrzut, Marcin Żmuda
Ginekol Pol 2008;79(6).

open access

Vol 79, No 6 (2008)
ARTICLES

Abstract

Abstract Objectives: The aim of the study was to evaluate the value of intraoperative assessment of depth of myometrial invasion in patients with FIGO stage I of the endometrial carcinoma. Material and methods: A total number of 112 patients with FIGO stage I of the endometrial carcinoma undergoing surgery were enrolled in the study. All patients had undergone intraoperative assessment of the depth of myometrial invasion performed by a surgeon. The depth was determined as more or less than 50% of myometrial thickness according to FIGO classification. Gross visual estimation of the depth of myometrial invasion at the time of the operation was compared with the final histopathological report. Sensitivity, specificity and positive and negative predictive values of the method were determined by means of statistical analyses. Results: The depth of the myometrial invasion was accurately determined by the surgeon in 82.1% of cases. Sensitivity and specificity were 68% and 82.1%, respectively. The accurate prediction rate of the myometrial invasion in the group of patients with well differentiated (G1) endometrial carcinoma was higher (88,4%) than in group with moderately and low differentiated tumour (78,3%). Conclusions: The accuracy of macroscopic evaluation of myometrial invasion is high and reaches up to 82,1%. The accurate determination rate increases if the differentiation of tumour is higher.

Abstract

Abstract Objectives: The aim of the study was to evaluate the value of intraoperative assessment of depth of myometrial invasion in patients with FIGO stage I of the endometrial carcinoma. Material and methods: A total number of 112 patients with FIGO stage I of the endometrial carcinoma undergoing surgery were enrolled in the study. All patients had undergone intraoperative assessment of the depth of myometrial invasion performed by a surgeon. The depth was determined as more or less than 50% of myometrial thickness according to FIGO classification. Gross visual estimation of the depth of myometrial invasion at the time of the operation was compared with the final histopathological report. Sensitivity, specificity and positive and negative predictive values of the method were determined by means of statistical analyses. Results: The depth of the myometrial invasion was accurately determined by the surgeon in 82.1% of cases. Sensitivity and specificity were 68% and 82.1%, respectively. The accurate prediction rate of the myometrial invasion in the group of patients with well differentiated (G1) endometrial carcinoma was higher (88,4%) than in group with moderately and low differentiated tumour (78,3%). Conclusions: The accuracy of macroscopic evaluation of myometrial invasion is high and reaches up to 82,1%. The accurate determination rate increases if the differentiation of tumour is higher.
Get Citation

Keywords

myometrium - invasion, endometrial carcinoma

About this article
Title

Value of the intraoperative assessment of the depth of myometrial invasion in endometrial carcinoma

Journal

Ginekologia Polska

Issue

Vol 79, No 6 (2008)

Bibliographic record

Ginekol Pol 2008;79(6).

Keywords

myometrium - invasion
endometrial carcinoma

Authors

Dariusz Ulman
Piotr Król
Andrzej Skręt
Joanna Skręt-Margieło
Marzanna Obrzut
Bogdan Obrzut
Marcin Żmuda

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl