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Vol 79, No 7 (2008)
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Thrombotic thrombocytopenic purpura in pregnancy. A case report

Krzysztof Chojnowski, Piotr Sieroszewski, Małgorzata Perenc, Jacek Treliński
Ginekol Pol 2008;79(7).

open access

Vol 79, No 7 (2008)
ARTICLES

Abstract

Abstract Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fetal death are frequent pregnancy complications of TTP. The following paper presents the case of a 32-year-old woman with TTP relapse at 10 weeks of her second pregnancy. Despite regular fresh frozen plasma transfusions, intrauterine fetal death occurred at 21 weeks of gestation. Current views on TTP management during pregnancy have been presented in the article as well.

Abstract

Abstract Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fetal death are frequent pregnancy complications of TTP. The following paper presents the case of a 32-year-old woman with TTP relapse at 10 weeks of her second pregnancy. Despite regular fresh frozen plasma transfusions, intrauterine fetal death occurred at 21 weeks of gestation. Current views on TTP management during pregnancy have been presented in the article as well.

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Keywords

treatment, pregnancy, Thrombotic thrombocytopenic purpura

About this article
Title

Thrombotic thrombocytopenic purpura in pregnancy. A case report

Journal

Ginekologia Polska

Issue

Vol 79, No 7 (2008)

Page views

654

Article views/downloads

567

Bibliographic record

Ginekol Pol 2008;79(7).

Keywords

treatment
pregnancy
Thrombotic thrombocytopenic purpura

Authors

Krzysztof Chojnowski
Piotr Sieroszewski
Małgorzata Perenc
Jacek Treliński

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